摘要
目的分析探讨丙硫氧嘧啶治疗妊娠期甲状腺功能亢进的临床疗效。方法选取本院2018年8月—2019年7月期间收治的88例妊娠期甲状腺功能亢进患者进行此次研究,按照数字表法将所有患者均分为参照组和观察组各44例。其中常规药物治疗的为参照组,使用丙硫氧嘧啶进行治疗的为观察组,观察比较两组患者的临床治疗成效、甲状腺功能指标以及对新生儿所产生的影响。结果治疗前,观察组和对照组患者的T3、T4和TSH水平差异无统计学意义(P>0.05);治疗后,观察组患者的T3、T4和TSH水平优于参照组,其差异具有统计学意义(P<0.05)。结论硫氧嘧啶能够在一定程度上优化妊娠期患者的甲状腺功能,提高临床治疗成效,并且不会对新生儿产生影响,有着一定的安全性。
Objective To analyze the efficacy and safety of propylthiouracil in the treatment of hyperthyroidism during pregnancy.Methods 88 cases of hyperthyroidism during pregnancy admitted to our hospital from August 2018 to July 2019 were selected for this study.All patients were divided into reference group and observation group with 44 cases in each according to the method of digital table.Among them,the control group was treated with conventional medicine,and the observation group was treated with propylthiouracil.Observe and compare the clinical treatment effect,thyroid function index and the impact on the newborn of the two groups.Results Before the treatment,there was no significant difference in T3,T4 and TSH levels between the observation group and the control group(P>0.05);after the treatment,the T3,T4 and TSH levels of the observation group were better than those of the reference group,the difference was statistically significant(P<0.05).Conclusion Thiouracil can optimize the thyroid function of pregnant women to a certain extent,improve the clinical treatment effect,and will not have an impact on the newborn,has a certain degree of safety,has the promotion value.
作者
裴慧琳
PEI Huilin(Department of Obstetrics and Gynecology,Daqing Oilfield General Hospital,Daqing Heilongjiang 163001,China)
出处
《中国卫生标准管理》
2020年第5期88-89,共2页
China Health Standard Management
