摘要
目的了解藏族农牧民梅毒螺旋体(TP)和乙型肝炎病毒(HBV)的感染情况,为传染病感染防控和健康教育工作提供依据。方法采集2018年3月至12月在朗县人民医院就诊和健康检查的藏族农牧民外周静脉血清,进行TP和HBV血清学检测,对结果进行统计学分析,追踪调查TP阳性患者基线资料。结果2440例藏族农牧民的梅毒抗体阳性率为2.34%,15~49岁组阳性率最高,其中婚前孕前筛查和孕产妇占总阳性人数接近50%,并发现新生儿和儿童感染病例。梅毒阳性患者基线资料调查中女性感染者多于男性,集中于15~49岁组的已婚人群,主要居住于偏远农牧区,以农民感染为主,文化程度偏低。人群HBsAg携带率为7.54%,随着年龄增长呈现逐步上升的趋势,以非活动性HBsAg携带者为主。HBsAb阳性率为20.70%,随着年龄的增长呈现逐步下降的趋势,71.43%的人群乙肝五项全部阴性。结论藏族农牧民TP和HBV感染率较高,人群乙肝免疫水平低,易感人群数量大,应加强人群传染性疾病预防接种干预和防治知识宣传教育。
Objective To study the prevalence of treponema pallidum(TP)and hepatitis B virus(HBV)in Tibetan farmers and herdsmen,so to provide a knowledge basis for prevention and control of infectious diseases and promote health education.Methods Peripheral venous serum was collected in Lang County People′s Hospital from March to December of 2018.Serological tests of TP and HBV were conducted and the results were statistically analyzed.Baseline data of TP positive patients was then followed up.Results The positive rate of TP antibody was 2.34%in 2440 Tibetan farmers and herdsmen and the highest one was the 15~49 years old group,among which pre-marital screening and pregnant women accounted for nearly 50%,and neonatal and child infection cases were discovered.Females were infected more than males in baseline data of TP positive patients,the most from married subjects with ages of 15-49,mainly living in remote agricultural and pastoral areas,and concentrated within farmers with low education level.The carrying rate of HBsAg was 7.54%in the population,which gradually increased with the growth of age,and mainly dominated by inactive HBsAg carriers.The positive rate of HBsAb was 20.70%,which gradually decreased with the growth of age,and 71.43%of HBV five serum marker were negative.Conclusion The infection rates of TP and HBV are high in Tibetan farmers and herdsmen,with low level of HBV immunity and large numbers of susceptible population.It is necessary to strengthen the education of vaccination interventions,prevention and treatment knowledge of infectious diseases.
作者
王春晖
曹碧红
廖惠贞
朱晓洁
索朗普尺
吴显劲
WANG Chunhui;CAO Bihong;LIAO Huizhen;ZHU Xiaojie;Suolangpuchi;WU Xian-jin(Inspection Center of Huizhou Municipal Central Hospital, Huizhou 516001, China;Department of Clinical Laboratory, Lang Country People’s Hospital, Lang Country 860400, China)
出处
《标记免疫分析与临床》
CAS
2020年第2期275-278,共4页
Labeled Immunoassays and Clinical Medicine
