摘要
目的了解白癜风患者甲病变的发生概率、类型等。方法收集2015年1月-2019年1月本院经治白癜风患者100例(观察组),另招募性别、年龄匹配的健康志愿者100例(对照组)。对比分析两组甲病变发生率和白癜风不同分型、分期间甲病变发生率。结果观察组甲病变总体发生率高于对照组,差异具有统计学意义(P<0.05)。观察组甲纵脊发生率高于对照组,差异具有统计学意义(P<0.05)。进展期白癜风甲病变发生率高于稳定期,差异具有统计学意义(P<0.05)。不同临床分型间甲病变发生率差异无统计学意义(P>0.05)。甲病变发生与发病年龄、病程间均无相关性(P均>0.05)。结论白癜风可见甲病变,以进展期白癜风多见,并常表现为甲纵脊。其发生无临床分型差异,且与发病年龄、病程均无相关性。
Objective To analyze the nail abnormalites in vitiligo patients.Methods One hundred vitiligo patients(observation group) treated in our hospital from January 2015 to January 2019 were enrolled,meanwhile 100 healthy volunteers were recruited(control group).The incidence of nail lesions in different groups and in different clinical phases or classification of vitiligo were compared.Results The overall incidence of nail lesions and longitudinal ridges in observation group were higher than those in control group(all P<0.05).The incidence of nail lesions in progress phase was higher than that in stable phase(P<0.05).There was no significant difference in the incidence of nail lesions among different clinical classifications(P>0.05).There was no correlation between the nail lesions and the on-set age or disease duration(P>0.05).Conclusion Nail longitudinal ridge is the most common manifestation,always in the progress phase.There is no difference among different clinical classification.No correlation between the nail leisions and on-set age or disease duration.
作者
毕晓东
陈日新
许丛丛
崔光静
BI Xiaodong;CHEN Rixin;XU Congcong;CUI Guangjing(Department of Dermatology,Hanyang First People's Hospital,Nanyang 473000,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2020年第4期405-408,共4页
The Chinese Journal of Dermatovenereology
关键词
白癜风
甲病变
发生率
Vitiligo
Nail lesions
Incidence
