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D-二聚体联合凝血四项对阴道分娩产后出血预测作用 被引量:12

The predictive effect of D-dimer combined with coagulation on postpartum hemorrhage during vaginal delivery
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摘要 将苏北人民医院经阴道分娩产妇200例分为产后出血组(观察组)与正常分娩组(对照组),比较两组产妇临产前的D-二聚体水平及凝血四项[凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)]水平,并分析上述指标在产后出血中的预测价值,探讨产前D-二聚体及凝血四项联合监测对阴道分娩产妇产后出血的临床意义。结果表明:D-二聚体、凝血四项水平与产后出血存在相关性,产后出血孕妇产前D-二聚体水平较正常分娩孕妇升高,PT、TT水平较正常下降,D-二聚体对产后出血具有中等预测价值,且与产后出血量存在线性关系。 We retrospectively analyzed 200 women undergoing vaginal delivery between November 2018 to June 2019 in Yangzhou Subei People’s hospital. Divided them into two groups, postpartum hemorrhage group(observation group) and normal childbirth group(control group). D-dimer level and blood coagulation four levels [prothrombin time(PT), activated partial clotting enzyme live time(APTT), thrombin time(TT), fibrinogen(FIB)] before they delivery were compared between two groups. We also analyzed the predictive value of the above indexes in postpartum hemorrhage. Results showed that D-dimer and clotting levels were correlated with postpartum hemorrhage. The levels of prenatal D-dimer in postpartum hemorrhage pregnant women were higher than normal pregnant women, while PT and TT levels were lower than normal pregnant women. D-dimer had medium predictive value for postpartum hemorrhage, and had a linear relationship with postpartum hemorrhage.
作者 钱天烨 郑皓文 曹佳晨 葛凡 徐金金 孔祥 QIAN Tianye;ZHENG Haowen;CAO Jiachen;GE Fan;XU Jinjin;KONG Xiang(College of Clinical Medicine,Yangzhou University,Yangzhou 225001,China)
出处 《扬州大学学报(农业与生命科学版)》 CAS 北大核心 2020年第1期33-36,43,共5页 Journal of Yangzhou University:Agricultural and Life Science Edition
基金 江苏省研究生科研与实践创新计划项目(XSJCX18-088) 扬州市社会发展(临床前沿)项目(YZ2017069)。
关键词 产妇 D-二聚体 凝血四项 产后出血 puerpera D-dimer coagulation four postpartum hemorrhage
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