摘要
目的研究分析高度近视患者准分子激光原位角膜磨镶术(laser-assisted in situ keratomileusis,LASIK)后屈光回退的危险因素,为临床预防高度近视患者LASIK术后屈光回退提供指导意见。方法选择2017年7月至2019年1月于我院眼科接受LASIK手术治疗的200例高度近视患者的临床资料进行回顾性研究,根据患者LASIK术后随访1年是否发生屈光回退,将患者分为屈光回退组与对照组。分析比较两组患者的临床资料,对导致高度近视患者LASIK术后屈光回退的危险因素进行单因素分析、多因素Logistics回归分析。结果在单因素分析中,屈光回退组与对照组在年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化方面比较,差异具有统计学意义(P<0.05),而屈光回退组与对照组在性别、病程、术后瞳孔变化、术后眼压变化方面比较,差异无统计学意义(P>0.05)。经多因素Logistics回归分析,年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化为高度近视患者LASIK术后屈光回退的危险因素(P<0.05)。结论年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化是导致高度近视患者LASIK术后发生屈光回退的危险因素,临床应根据LASIK术后屈光回退危险因素采取针对性预防干预。
Objective To study and analyze the risk factors of refractive regression after laser-assisted in situ keratomileusis(LASIK)in patients with high myopia,and to provide guidance for clinical prevention of refractive regression after LASIK in patients with high myopia.Methods From July 2017 to January 2019,the clinical data of 200 patients with high myopia who underwent LASIK in ophthalmology department of our hospital were selected for a retrospective study.According to whether or not refractive regression occurred after 1 year follow-up after LASIK,the patients were divided into refractive regression group and control group.The clinical data of the two groups were analyzed and compared,and the risk factors of refractive regression after LASIK in patients with high myopia were analyzed by univariate analysis and multivariate Logistic analysis.Results In the univariate analysis,there were significant differences in age,preoperative axial length,preoperative refractive power and postoperative central corneal thickness change between the refractive regression group and the control group(P<0.05),while there were no significant differences in gender,course of disease,postoperative pupil change and intraocular pressure change between the refractive regression group and the control group(P>0.05).The multivariate Logistic analysis showed that age,preoperative axial length,preoperative refractive power and postoperative central corneal thickness change were the risk factors of refractive regression in high myopia patients after LASIK(P<0.05).Conclusion Age,preoperative axial length,preoperative refractive power and postoperative central corneal thickness are the risk factors of refractive regression in patients with high myopia after LASIK.The clinical prevention and intervention should be taken according to the risk factors of refractive regression after LASIK.
作者
陈蒙
CHEN Meng(Refraction Center,Xi'an Cunji Medical Center,Xi'an 710032,China)
出处
《临床医学研究与实践》
2020年第10期10-12,共3页
Clinical Research and Practice
关键词
高度近视
激光原位角膜磨镶术
屈光回退
眼轴长度
屈光度数
角膜中央厚度
high myopia
laser-assisted in situ keratomileusis
refractive regression
axial length
refractive power
central corneal thickness
