托拉塞米联合多巴胺治疗顽固性心力衰竭的临床疗效被引量：4

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摘要目的探讨托拉塞米联合多巴胺治疗顽固性心力衰竭(RHF)的临床疗效。方法选取武汉市第九医院2017年10月—2018年8月收治的RHF患者76例,采用随机数字表法分为对照组和观察组,各38例。对照组给予托拉塞米治疗,观察组在对照组基础上给予多巴胺治疗,两组均连续治疗7 d。比较两组临床疗效,治疗前后左心舒张末期内径(LVEDD)、左心室射血分数(LVEF)、白介素6(IL-6)、肿瘤坏死因子α(TNF-α)。结果观察组总有效率高于对照组(P<0.05)。治疗前两组LVEDD、LVEF、IL-6、TNF-α比较,差异无统计学意义(P>0.05);治疗后观察组LVEDD、IL-6、TNF-α低于对照组,LVEF高于对照组(P<0.01)。结论托拉塞米联合多巴胺治疗RHF的临床疗效确切,可有效改善心脏射血功能,具有减轻心肌损伤、延缓心肌重构作用。

作者郑伟张丽

机构地区湖北省武汉市第九医院急诊内科湖北省武汉市第九医院神经内科

出处《临床合理用药杂志》 2020年第6期45-46,共2页 Chinese Journal of Clinical Rational Drug Use

关键词心力衰竭托拉塞米多巴胺治疗结果

分类号 R541.6 [医药卫生—心血管疾病]

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