摘要
目的调查广东、广西、福建、湖南4个省份精神专科医院或开设精神科的综合性医院的治疗药物监测(TDM)实施情况。方法采用在线问卷调查形式开展调研,回收的问卷通过可信度评判后方可参与统计。结果共回收有效问卷69份,其中已开展TDM的有39家,35.9%开展TDM的受访医院参与室间质评,由药学部门开展的TDM中,37.5%和50.0%分别对全部和部分异常值进行临床干预,而由检验科开展的TDM,该数据分别为16.7%和30.0%。结论TDM应有临床药学人员的参与,由检测部门、临床药学和临床医师共同为患者实现个体化药物治疗。
Objective To investigate the development of therapeutic drug monitoring(TDM)in psychiatric hospitals or general hospitals with psychiatric department of Guangdong,Guangxi,Fujian and Hunan pro-vince.Methods The investigation was conducted through online questionnaire.The recovery questionnaires should have passed a feasibility evaluation before involved in the statistical analysis.Results Sixty-nine valid questionnaires were recovered,in which 39 hospitals have offered TDM.And 35.9%of the 39 hospitals with psychiatric TDM participated external quality assessment.In the TDM conducted by pharmaceutical departments,37.5%and 50.0%were offered clinical intervention for total and partial abnormal results,respectively,while the data conducted by clinical laboratories were 16.7%and 30.0%,respectively.Conclusion Clinical pharmacists should participate TDM.Individualized drug therapy should be conducted by the cooperation of laboratory,clinical pharmacists and clinicians.
作者
卢浩扬
温预关
谢煥山
陈宏镇
倪晓佳
尚德为
王占璋
LU Hao-yang;WEN Yu-guan;XIE Huan-shan;CHEN Hong-zhen;NI Xiao-jia;SHANG De-wei;WANG Zhan-zhang(Department of Pharmacy,Guangzhou Huiai Hospital,The Affiliated Brain Hospital of Guangzhou Medical University,Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders,Guangzhou 510370,Guangdong Province,China)
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2020年第6期712-713,721,共3页
The Chinese Journal of Clinical Pharmacology
基金
2018年广东省卫生计生适宜技术推广基金资助项目(粤卫办函[2018]326号-18)
广州市科技计划项目创新平台建设计划基金资助项目(201805010009)
广州市医学重点学科基金资助项目(2017-2019)
广东省省级科技计划基金资助项目(2019B030316001)。
关键词
华南
精神科
治疗药物监测
调查
South China
psychiatric
therapeutic drug monitoring
investigation
