摘要
目的研究血芙蓉Teucrium viscidum Bl.的化学成分。方法血芙蓉70%乙醇提取物采用硅胶、ODS、Sephadex LH-20凝胶柱进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到20个化合物,分别鉴定为20β-羟基熊果酸(1)、β-谷甾醇(2)、羽扇豆醇(3)、齐墩果酸(4)、木犀草素(5)、槲皮素(6)、芹菜素(7)、β-胡萝卜苷(8)、芹菜素-7-O-β-D-葡萄糖苷(9)、teuvisone (10)、lipidiol (11)、teucvisin B (12)、1,5,9-epideoxyloganin (13)、1,5,9-epideoxyloganic acid (14)、5-epideoxyloganin (15)、argylioside (16)、8-epideoxyloganic acid (17)、radiatoside E (18)、radiatoside F (19)、enmenol-glucoside (20)。结论化合物1、3、7、9、13~20为首次从该植物中分离得到,化合物1、13~20为首次从石蚕属植物中分离得到。
AIM To study the chemical constituents from Teucrium viscidum Bl. METHODS The 70%ethanol extract from T. viscidum was isolated and purified by silica,ODS and Sephadex LH-20,then the structures of obtained compounds were identified by physicochemical properties and spectral data. RESULTS Twenty compounds were isolated and identified as 20β-hydroxy ursolic acid( 1),β-sitosterol( 2),lupenol( 3),oleanolic acid(4),luteolin( 5),quercetin( 6),apigenin( 7),β-daucosterol( 8),apigenin-7-O-β-D-glucoside( 9),teuvisone(10),lipidiol(11),teucvisin B(12),1,5,9-epideoxyloganin(13),1,5,9-epideoxyloganic acid(14),5-epideoxyloganin(15),argylioside(16),8-epideoxyloganic acid(17),radiatoside E(18),radiatoside F(19),enmenol-glucoside(20). CONCLUSION Compounds 1,3,7,9,13-20 are isolated from this plant for the first time,and compounds 1,13-20 are isolated from genus Teucrium for the first time.
作者
孙志青
刘立云
孙岩
黄胜阳
SUN Zhi qing;LIU Li yun;SUN Yan;HUANG Sheng yang(Beijing Key Laboratory of Environmental and Viral Oncology,College of Life Science and Bioengineering,Beijing University of Technology,Beijing 100124,China)
出处
《中成药》
CAS
CSCD
北大核心
2020年第4期932-938,共7页
Chinese Traditional Patent Medicine
关键词
血芙蓉
化学成分
分离鉴定
Teucrium viscidum Bl.
chemical constituents
isolation and identification
