摘要
目的:探讨莫沙必利联合半夏泻心汤对糖尿病胃轻瘫患者血清胃肠激素水平的影响及疗效。方法:2016年3月-2018年3月收治糖尿病胃轻瘫患者88例,随机分为两组,各44例。对照给予莫沙必利进行治疗;试验组在给予莫沙必利的同时加半夏泻心汤治疗。比较两组患者临床疗效和治疗前后血清胃动素(MTL)和生长抑素(SS)水平的变化。结果:试验组治疗总有效率优于对照组,两组治疗后两组MTL和SS水平均有改善,但试验组改善程度更优,差异均有统计学意义(P<0.05)。结论:莫沙必利和半夏泻心汤联合治疗糖尿病胃轻瘫患者效果显著,可明显降低MTL,使SS水平增高,对胃肠激素紊乱进行调整,恢复胃蠕动功能。
Objective:To explore the effect of mosapride combined with banxia xiexin decoction on the level of serum gastrointestinal hormones in patients with diabetic gastroparesis.Methods:88 patients with diabetic gastroparesis were selected from March 2016 to March 2018,they were randomly divided into the two groups with 44 cases in each group.The control group was treated with mosapride,the experimental group was treated with mosapride combined with banxia xiexin decoction.The clinical effect and the changes of serum motilin(MTL)and somatostatin(SS)before and after treatment were compared between the two groups.Results:The total effective rate of treatment in the experimental group was better than that in the control group.Both MTL and SS levels improved after treatment in both groups,but the degree of improvement in the experimental group was better,and the differences were statistically significant(P<0.05).Conclusion:The combination of mosapride and banxia xiexin decoction is a safe and effective treatment for diabetic gastroparesis,which can significantly reduce serum gastrointestinal hormone,increase SS level,adjust gastrointestinal hormone disorder and restore gastric peristalsis function.
作者
余蓉
Yu Rong(Hunan Wangwang Hospital,Hunan Changsha 410016)
出处
《中国社区医师》
2020年第13期95-95,97,共2页
Chinese Community Doctors
关键词
莫沙必利
半夏泻心汤
糖尿病
胃轻瘫
血清胃肠激素
Moshabili
Banxia xiexin decoction
Diabetes
Gastroparesis
Serum gastrointestinal hormone
