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TCCD检测大脑中动脉闭塞患者脑血流的临床意义 被引量:3

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摘要 目的:探讨经颅彩色多普勒超声(TCCD)检测单侧慢性大脑中动脉闭塞(CMCAO)患者脑血流的临床意义。方法:收集2016年7月至2019年8月在我院就诊行TCCD检查诊断为一侧MCAO而对侧MCA正常,并经DSA证实的患者84例。根据CT或MRI结果分为患侧MCA供血区新发脑梗死组(CI)39例,无脑梗死组(NCI)45例。根据DSA显示分为ACA脑膜支代偿组(LAMACA)39例,无ACA脑膜支代偿组(NLAMACA)45例;PCA脑膜支代偿组(LAMPCA)28例,无PCA脑膜支代偿组(NLAMPCA)56例。通过TCCD检测并记录患者患侧(i)与健侧(c)大脑中动脉(MCA)、大脑前动脉(ACA)及大脑后动脉(PCA)的收缩期峰值流速(PSV)和平均流速(MV),并计算健侧与患侧MCA、ACA、PCA 的MV比值(MVcMCA/MViMCA、MViACA/MVcACA、MViPCA/MVcPCA)。结果:①NCI组PSViMCA、MViMCA、PSViACA、MViACA、MViACA/MVcACA较CI组均升高,差异有统计学意义(P<0.05)。②LAMACA组PSViACA、MViACA、MViACA/MVcACA均高于NLAMACA组,LAMPCA组PSViPCA、MViPCA、MViPCA/MVcPCA均高于NLAMPCA组,差异有统计学意义(P<0.05)。③PSViMCA、MViMCA、PSViACA、MViACA、MViACA/MVcACA与脑梗死的发生均呈负相关(r=-0.257,P=0.018;r=-0.286,P=0.008;r=-0.392,P=0.000;r=-0.388,P=0.000;r=-0.269,P=0.013)。④PSViACA、MViACA、MViACA/MVcACA与ACA脑膜支代偿均呈正相关(r=0.778,P=0.000;r=0.766,P=0.000;r=0.554,P=0.000),PSViPCA、MViPCA、MViPCA/MVcPCA数与PCA脑膜支代偿均呈正相关(r=0.683,P=0.000;r=0.675,P=0.000;r=0.575,P=0.000)。结论:通过TCCD检测MCA、ACA、PCA血流动力学变化,可以间接评估CMCAO软脑膜支的代偿情况,客观评价CMCAO患者脑组织灌注信息,为其临床治疗方法的选择及疗效的判断提供客观依据。
出处 《影像研究与医学应用》 2020年第9期198-201,共4页 Journal of Imaging Research and Medical Applications
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