摘要
20世纪70年代,Framingham研究发现吸烟可增加卒中风险。之后的实验室和临床研究证实,烟草中的多种有害成分会损害血管内皮、干扰凝血机制,导致动脉粥样硬化和血液高凝状态,最终引发卒中。另外,烟草中的有害成分还会诱发高血压、糖尿病、房颤等疾病,从而间接增加卒中风险。但在吸烟与卒中关系方面,仍然存在大量问题有待研究。文中将分析吸烟与卒中的相关性及其机制,同时探讨戒烟对于卒中预后的影响,以期为相关疾病的防治提供参考。
In the 1970s,the Framingham study found that smoking increased the risk of stroke.Subsequent laboratory and clinical studies have demonstrated that a variety of harmful components in tobacco can damage the vascular endothelium and interfere with the clotting mechanism,giving rise to atherosclerosis and hypercoagulability,which eventually leads to stroke.Furthermore,the harmful ingredients in tobacco may induce hypertension,diabetes,atrial fibrillation and other diseases,which indirectly increase the risk of stroke.However,there are still a lot of questions about the relationship between smoking and stroke.This paper will analyze the correlation between them and its mechanism,and discuss the influence of smoking cessation on the prognosis of stroke,so as to provide reference for the prevention and treatment of related diseases.
作者
陈晶晶
徐格林
CHEN Jing-jing;XU Ge-lin(Department of Neurology,General Hospital of Eastern Theater Command,PLA,Nanjing 210002,Jiangsu,China)
出处
《医学研究生学报》
CAS
北大核心
2020年第5期454-459,共6页
Journal of Medical Postgraduates
