摘要
目的研究布托啡诺用于胫腓骨切开复位内固定患者的临床效果。方法选取2017年4月~2019年6月承德医学院附属医院收治的需行胫腓骨切开复位内固定患者80例,应用随机数表法分为布托啡诺组(40例)和生理盐水对照组(40例)。布托啡诺组采用布托啡诺2 mg(2 ml)+生理盐水(8 ml),共10 ml;生理盐水对照组采用生理盐水10 ml。两组患者药物均泵注10 min后行腰丛联合坐骨神经阻滞。观察患者内固定手术期间的心率、平均动脉压和镇静评分,以及手术结束后的镇痛评分和不良反应情况。结果布托啡诺组的血流动力学指标、镇静评分和镇痛评分都优于生理盐水对照组,差异有统计学意义(P<0.05),无明显不良反应的发生。结论布托啡诺用于胫腓骨切开复位内固定患者能够维持稳定的血流动力学水平,同时还有良好的镇静和超前镇痛作用。
Objective To study the clinical effect of butorphanol in patients with open reduction and internal fixation of tibia-fibula fracture.Methods According to the random number table,Eighty patients with open reduction and internal fixation of tibia-fibula fracture were divided into butorphanol group B(group B,n=40)and saline control group(group N,n=40).Group B:butorphanol 2 mg(2 ml)+normal saline(8 ml),a total of 10 ml.Group N:10 ml of normal saline.The infusion time was 10 minutes,and combined lumbar plexus-sciatic nerve block was administered 10 minutes after the end of drug pumping.The heart rate,mean arterial pressure and sedation scores during the internal fixation surgery,as well as the analgesic score and adverse reactions after the operation were observed.Results The hemodynamic parameters,sedation score and analgesia score of the butorphanol group were better than those of the normal saline control group(P<0.05),and no significant adverse reactions occurred.Conclusion Butorphanol can maintain stable hemodynamic level in patients with open reduction and internal fixation of tibia-fibula fracture,and also has good sedation and advanced analgesia.
作者
刘燃
刘海旺
李玲
李艳
宋莺春
董家玮
Liu Ran;Liu Haiwang;Li Ling(Department of Anesthesiology,the Affiliated Hospital of Chengde Medical College,Chengde 067000,China)
出处
《中华保健医学杂志》
2020年第2期147-149,共3页
Chinese Journal of Health Care and Medicine
基金
承德市科技支撑计划项目(201701A081)。
关键词
布托啡诺
超前镇痛
神经阻滞
Butorphanol
Preemptive analgesic
Nerve block
