摘要
成人Still病(AOSD)是一种发病率低且病因未明的全身炎性反应性疾病。AOSD的主要表现为发热、皮疹、咽痛和关节痛,但临床表现及预后差异性大。AOSD缺乏特异的血清学和病理学表现,诊断及治疗主要依靠经验。而早期诊断、治疗及良好的疾病监测对于疾病的转归具有积极意义。文章主要就AOSD的实验室、影像学检查,疾病活动度监测,生物制剂应用的研究进展作一综述。
Adult Still’s disease(AOSD)is a systemic inflammatory response disease with low incidence rate and unknown etiology.The main manifestations of AOSD were fever,rash,pharyngeal pain and arthralgia,but there were significant differences in clinical manifestations and prognosis.AOSD lacks specific serological and pathological manifestations,and its diagnosis and treatment mainly depend on experience.Early diagnosis,treatment and good disease monitoring are of positive significance for the prognosis of the disease.This paper mainly reviews the research progress of AOSD in laboratory,imaging examination,disease activity monitoring,and application of biological agents.
作者
李施阳(综述)
张晓莉(审校)
LI Shiyang;Zhang Xiaoli(Department of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Liaoning Province,Shenyang 110004, China)
出处
《疑难病杂志》
CAS
2020年第5期537-540,共4页
Chinese Journal of Difficult and Complicated Cases
基金
辽宁省科学技术研究计划项目(2015020546)。
