摘要
背景维生素D不仅影响骨代谢,还在免疫调节、维持神经系统功能、预防心血管疾病、肿瘤、代谢性疾病等方面发挥重要作用。因此,研究儿童维生素D营养状况与性别、年龄、季节、民族及健康状态的关系,对预防儿童维生素D缺乏及相关疾病具有重要意义。目的研究内蒙古0~14岁儿童维生素D营养状况与性别、年龄、季节、民族及健康状态的关系。方法回顾性分析2018年1—12月在内蒙古呼伦贝尔市人民医院儿科进行维生素D检测的7963例0~14岁儿童的临床资料和血清25羟维生素D〔25-(OH)-D〕水平。结果不同性别儿童25-(OH)-D水平比较,差异无统计学意义(P>0.05)。不同年龄儿童25-(OH)-D水平比较,差异有统计学意义,事后检验显示婴幼儿>学龄前>学龄儿(P<0.05)。血清25-(OH)-D水平在婴儿期随月龄增长逐渐升高,至6月龄后达到较高水平,持续至12月后随年龄增长逐渐下降。各季节婴幼儿血清25-(OH)-D水平比较,差异无统计学意义(P>0.05);其他年龄组夏季最高,其次为秋季,冬春季较低(P<0.05)。汉族婴幼儿血清25-(OH)-D水平高于少数民族,差异有统计学意义(P<0.05);学龄儿与学龄前年龄组的汉族与少数民族血清25-(OH)-D水平比较,差异无统计学意义(P>0.05)。健康的学龄前儿童、婴幼儿血清25-(OH)-D水平高于患病儿,差异有统计学意义(P<0.05);学龄儿是否健康血清25-(OH)-D水平比较,差异无统计学意义(P>0.05)。结论内蒙古0~14岁儿童维生素D营养状况与性别无关,与年龄、季节、民族及健康状态有关。
Background Vitamin D plays an important role not only in bone metabolism,but also in immune regulation,the maintenance of nervous system function,and the prevention of cardiovascular diseases,tumors and metabolic diseases.Therefore,it is of great significance to study the relationship between children's vitamin D status and gender,age,season,nationality and health status to prevent vitamin D deficiency in children.Objective To study the relationship between nutritional status of vitamin D and gender,age,season,nationality and health status in children aged 0-14.Methods The clinical data and serum 25-(OH)-D level of 7963 children aged 0-14 who were tested for vitamin D in Department of Pediatrics of Hulunbeir People's Hospital in Inner Mongolia from January to December in 2018 were analyzed retrospectively.Results There was no significant difference in the level of 25-(OH)-D between children with different genders(P>0.05).The difference of 25-(OH)-D levels among children with different ages was statistically significant,and the back testing showed that 25-(OH)-D level was highest in infants,followed by preschool children,and lowest in school-age children(P<0.05).Serum 25-(OH)-D level gradually increased with the increase of the month of age in infancy,and reached a high level at six months,which lasted for next six months and then gradually decreased with age.There was no significant difference in serum 25-(OH)-D level among infants in different seasons.School-age children and preschool children had the highest serum 25-(OH)-D level in summer,followed by autumn,winter and spring.The 25-(OH)-D level of infants of Han nationality was higher than that of infants of other minorities,and the difference was statistically significant(P<0.05),while there was no statistical difference in serum 25-(OH)-D levels between Han nationality and other minorities among school-age children and preschool children(P>0.05).The levels of serum 25-(OH)-D in healthy preschool children and infants were higher than those in diseased children,and the difference was statistically significant(P<0.05).There was no significant difference in serum 25-(OH)-D levels between diseased school-age children and healthy school-age children(P>0.05).Conclusion The vitamin D status of children aged 0-14 in Inner Mongolia has nothing to do with gender,but is related to age,season,nationality and health status.
作者
曲建平
陈桂梅
宋玉伟
QU Jianping;CHEN Guimei;SONG Yuwei(Department of Pediatrics,Hulunbeir People's Hospital,Hulunbeir 021008,China)
出处
《中国全科医学》
CAS
北大核心
2020年第22期2820-2824,共5页
Chinese General Practice
