摘要
目的探讨湖北省荆门地区的泌尿系结石成分特征,为临床治疗和诊断提供参考。方法选取荆门市第一人民医院、沙洋县人民医院、钟祥市人民医院和京山县人民医院四院泌尿外科于2016年1月至2018年12月间收治的患者资料,将符合标准的2000例患者纳入研究,使用红外光谱法检测其结石成分,并结合患者一般资料进行分析。结果泌尿系结石患者中50~65岁人群患病率最高,为46.60%(932/2000);男性患者1297例(64.85%),为女性患者的1.85倍;其中≤12岁和>75岁患者中的男女比例比值最大,为3∶1。结石主要位于肾脏和输尿管,膀胱占比较少,尿道不常见。结石成分主要草酸钙,其次为碳酸磷灰石和尿酸类,胱氨酸和磷酸铵镁结石不常见;仅在女性患者中发现羟基磷灰石和磷酸氢钙结石(占0.5%~0.7%),同时女性磷酸铵镁成分明显比男性常见(P<0.001)。首发和复发患者结石成分占比大体相似,草酸钙结石占大部分,碳酸磷灰石结石常见,尿酸类和磷酸铵镁结石出现率不高,胱氨酸、羟基磷灰石和磷酸氢钙结石不常见。结论湖北省荆门地区泌尿系结石草酸钙成分和肾脏发病最为常见,男女结石部分成分存在差异,可为该地区临床针对性预防和治疗提供参考。
Objective To analyze the composition and characteristics of urinary stones in Jingmen area of Hubei province,and provide reference for clinical treatment and diagnosis.Methods The patient data of the department of urology,Jingmen first people's hospital,Shayang county people's hospital,Zhongxiang people's hospital and Jingshan county people's hospital from January 2016 to December 2018 were screened.A total of 2000 patients were enrolled in the study,and their composition was determined by infrared spectroscopy and combined with general patient data.Results Among the patients with urinary calculi,the prevalence rate was the highest among the 50-65 year old,which was 46.60%.The male was more than the female,1297 cases(64.85%),and the female was 1.85 times.Among them,the ratio of male to female was the highest in patients aged less than or equal to 12 years old and older than 75 years old,which was 3∶1.The stones were mainly located in the kidney and ureter,the bladder was less,and the urethra was not common.The main components of the stone were calcium oxalate,followed by carbonate apatite and uric acid.The cystine and ammonium ammonium phosphate stones were not common.Hydroxyapatite and calcium hydrogen phosphate stones were found only in female patients(about 0.5%-0.7%).At the same time,female magnesium ammonium phosphate was significantly more common than males(P<0.001).The proportion of stones in primary and recurrent patients was similar,calcium oxalate stones account for the majority,carbonate apatite stones were common,uric acid and magnesium ammonium phosphate stones were not high,cystine,hydroxyapatite and calcium hydrogen phosphate stones uncommon.Conclusions The urinary calculi in the Jingmen area of Hubei province is the most common form of calcium oxalate and kidney disease.There are differences in the components of male and female stones,which can provide reference for clinical targeted prevention and treatment in this area.
作者
王超
蔡勇
杨荣权
刘周强
李壮志
李波
李俊平
阳磊
廖泽明
Wang Chao;Cai Yong;Yang Rongquan;Liu Zhouqiang;Li Zhuangzhi;Li Bo;Li Junping;Yang Lei;Liao Zeming(Department of Urology,the First People's Hospital of Jingmen,Jingmen 448000,China)
出处
《国际泌尿系统杂志》
2020年第3期448-452,共5页
International Journal of Urology and Nephrology
基金
荆门市科技计划项目(YFZD2015050)。
关键词
尿路结石
湖北
主成分分析
Urinary Calculi
HUBEI
Principal Component Analysis
