摘要
鸡传染性支气管炎(IB)是由传染性支气管炎病毒(IBV)引起的一种高度接触性传染病。IBV可引起鸡呼吸道、肾脏和生殖道等部位病变,并造成死亡,给养鸡业造成巨大的经济损失。由于不同基因型的IBV在组织嗜性和致病性方面有着较大的差异,且不同血清型/基因型之间交叉保护性低,因此,新IBV血清型/基因型的不断出现给本病的防控带来困难。论文综述了鸡传染性支气管炎病原学、流行与分布、分子遗传变异机制、IBV诱导的天然免疫应答、体外培养、诊断技术和防控措施等的研究进展,旨在为IB的相关研究提供理论依据和防控策略。
Infectious bronchitis(IB)is a highly contagious disease caused by infectious bronchitis virus(IBV).IBV can cause lesions in the respiratory tract,kidneys and reproductive tract of chickens,and cause death,causing huge economic losses to the chicken industry.Because different genotypes of IBV have differences in tissue tropism and pathogenicity,and cross-protection between different serotypes or genotypes is low.Therefore,the continuous emergence of new IBV serotypes or genotypes brings difficulties to the prevention and control of IB.This paper summarized the research progress on etiology,epidemiology,molecular genetic variation mechanism,IBV-induced innate immune response,in vitro culture,diagnostic techniques and prevention and control measures of IBV in recent years.The purpose of this paper is to provide a theoretical basis and prevention and control strategy for the study of the relevant mechanism of IBV.
作者
李桂明
潘力
于可响
路晓
董雯雯
唐亮
许蔷
林树乾
王林
LI Gui-ming;PAN Li;YU Ke-xiang;LU Xiao;DONG Wen-wen;TANG Liang;XU Qiang;LIN Shu-qian;WANG-Lin(Institute of Poultry,Shandong Academy of Agricultural Sciences,Jinan,Shandong,250023,China;College of Animal Science and Technology,Shandong Agricultural University,Tai'an,Shandong,271018,China)
出处
《动物医学进展》
北大核心
2020年第5期111-115,共5页
Progress In Veterinary Medicine
基金
国家重点研发计划项目(2017YFC1702700)
山东省自然科学基金项目(ZR2019MC022)
山东省重点研发计划项目(2019LYX2018)
济南市自主创新团队项目(2019GXRC025)
山东省农业科学院创新工程项目(CXGC2016B14)
山东省农业科学院农业科技创新工程项目(CXGC2016A10)。
关键词
鸡传染性支气管炎病毒
病原学
变异机制
免疫应答
Avian infectious bronchitis virus
etiology
variation mechanism
immune response
