摘要
目的探索运动干预胰岛素的研究前沿和热点。方法采用文献计量学方法,收集Web of Science已发表的相关文献,基于CiteSpace V软件进行可视化分析。结果1992-2018年,运动干预胰岛素的发文量为14989篇,其中与外源性胰岛素相关的只有129篇;Richter EA和Defronzo RA分别是该领域领先的高产作者和被引作者,哥本哈根大学是目前产出最多的研究机构。胰岛素抵抗、骨骼肌、肥胖、胰岛素敏感性和代谢综合征是该领域的高频共现关键词,炎症、有氧运动、氧化应激和抗阻运动等是近年的爆发性关键词。结论运动对胰岛素生物学的干预是研究热点,运动对胰岛素临床应用的安全性和有效性应该引起研究者的关注。
Objective To explore the frontiers and hotspots of exercise intervention of insulin.Methods Bibliometric analysis was used to collect relevant papers published by Web of Science and the visualization was analyzed based on CiteSpace V software.Results There were 14989 articles about exercise intervention of insulin were collected,129 of which were related to exogenous insulin from 1992 to 2018.Richter EA and Defronzo RA were the first prolific author and the first cited author in this field,respectively.Copenhagen University was the most productive research institution.Insulin resistance,skeletal muscle,obesity,insulin sensitivity and metabolic syndrome were the high frequency keywords in this field,while inflammation,aerobic exercise,oxidative stress and resistance exercise were the burst keywords in recent years.Conclusion The intervention of exercise on the biology of insulin is a research hotspot.Attention should be paid to the safety and efficacy of exercise on the clinical application of insulin.
作者
李茜茜
郭姗姗
郭建军
赵志刚
LI Xi-xi;GUO Shan-shan;GUO Jian-jun;ZHAO Zhi-gang(School of Pharmaceutical Sciences,Capital Medical University,Beijing 100069;Department of Pharmacy,Beijing Tiantan Hospital Affiliated to Capital Medical University,Beijing 100070;Integration of Exercise and Medicine Research Center,Capital University of Physical Education and Sports,Beijing 100191)
出处
《中南药学》
CAS
2020年第5期882-887,共6页
Central South Pharmacy
基金
创新驱动工程-体医融合产业协同创新助推健康中国战略实施(No.ZLGC201901-14)。
