摘要
近几年来针对精神分裂症和氧化应激的关联,有国内外学者进行了大量研究和实践。现对氧化应激在精神分裂症发病机制中的作用以及非酶类抗氧化物对精神分裂症的可能影响的相关文献进行归纳,分析抗氧化剂在抗氧化防御系统中的影响和与精神分裂症的相关性,进一步拓宽对精神分裂症的认识,为探讨精神分裂症的治疗新方法提供理论基础。
In recent years,a large number of studies and practices have been conducted on the relationship between schizophrenia and oxidative stress.This review summarizes the related literature on the role of oxidative stress in the pathogenesis of schizophrenia and the possible effects of non-enzymatic antioxidants on schizophrenia,analyzes the effect of antioxidants on the antioxidant defense system and its correlation with schizophrenia,thus further broadening our understanding of schizophrenia and providing a theoretical basis for the development of novel treatment of schizophrenia.
作者
房策
曾波涛
Fang Ce;Zeng Botao(The 14th School of Clinical Medicine,Qingdao University,Qingdao 266000,China;Psychology Department,Qingdao Youfu Hospital,Qingdao 266071,China;Department of Clinical Psychology,Mental Health Center of Qingdao,Qingdao 266034,China)
出处
《神经疾病与精神卫生》
2020年第2期142-147,共6页
Journal of Neuroscience and Mental Health
基金
山东省医药卫生科技发展计划项目(2017WS115)
青岛市医药科研指导计划(2016-WJZD068)。
关键词
精神分裂症
氧化应激
非酶类抗氧化物
活性物质
综述
Schizophrenia
Oxidative stress
Non-enzymatic antioxidants
Active substance
Review
