摘要
目的:研究党参药材中化学成分在不同湿度下随时间的变化规律,为党参药材的化学质量稳定性提供数据支持。方法:以甘肃省岷县党参药材规范化种植基地种植的党参药材为研究对象,设置常湿、20%、5%3种不同的湿度,同时测定其中党参炔苷、多糖、葡萄糖、果糖和蔗糖的含量在6个月内的变化情况。结果:在6个月内,不同湿度下党参炔苷的含量呈现不同程度的下降趋势。多糖、蔗糖、葡萄糖和果糖的含量均呈现出不同程度先升高再降低的趋势。不同湿度对党参药材化学质量稳定性的影响程度不同,依次为5%>20%>常湿,即5%湿度下党参药材的化学质量稳定性最佳。结论:该研究提示湿度对党参药材中化学成分的含量有较大的影响,进而影响到党参药材化学质量的稳定性。在实际生产实践过程中,应严格控制党参药材的储藏湿度,以期保证党参药材质量的稳定可靠,为临床用药的有效性奠定基础。
Objective:The aim of this study was to analyze the changes in chemical constituents at different humidities and provide references for the quality stability of Codonopsis Radix.Methods:The content of lobetyolin,polysaccharide,sucrose,glucose and fructose of Codonopsis Radix samples stored at 3 kinds of different humidities including normal humidity,20%,5%was detected for 6 months simultaneously.Results:The results indicated that the content of lobetyolin decreased in different degree while that of polysaccharide,sucrose,glucose and fructose showed a tendency of first rise then fall during 6 months.Different humidities had influences on the quality stability of Codonopsis Radix at various degree,that was 5%>20%>normal humidity in turn.It was optimum to adopt humidity of 5%to ensure a good quality of Codonopsis Radix.Conlusion:Our ndings demonstrated that humidity had an obvious impact on chemical constituents of Codonopsis Radix,which should be strictly controlled to ensure the quality stability of Codonopsis Radix and guarantee its validity of clinical treatment.
作者
高石曼
刘久石
王敏
曹婷婷
齐耀东
张本刚
刘海涛
孙晓波
肖培根
GAO Shi-man;LIU Jiu-shi;WANG Min;CAO Ting-ting;QI Yao-dong;ZHANG Ben-gang;LIU Hai-tao;SUN Xiao-bo;XIAO Pei-gen(Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing100193,China)
出处
《中国现代中药》
CAS
2020年第4期596-602,共7页
Modern Chinese Medicine
基金
首都市民健康项目培育(Z161100000116101)
中国医学科学院医学与健康科技创新工程项目(2016-12M-1-010)。
关键词
党参
化学质量
稳定性
湿度
Codonopsis Radix
Quality
Stability
Humidity
