摘要
目的探讨消化内镜联合四联方案治疗胃溃疡出血的临床疗效及再出血因素。方法选择我院100例2017年1月至2018年2月胃溃疡出血患者。随机分组,对照组采取四联方案治疗,药物内镜组则采取四联方案+消化内镜治疗。比较两组胃溃疡出血疗效;溃疡面积缩小一半时间、快速尿素酶试验转阴时间、溃疡愈合时间;治疗前后患者症状积分情况;再出血因素。结果药物内镜组有更高的疗效,P<0.05。药物内镜组总有效率100%;对照组总有效率80%。治疗前对照组、药物内镜组症状积分情况比较,P>0.05;治疗后药物内镜组症状积分情况变化幅度更大,P<0.05。其中,对照组治疗前症状积分是(3.26±1.53)分,而治疗后是(1.67±0.67)分。药物内镜组症状积分是(3.24±1.56)分,而治疗后是(0.51±0.21)分。药物内镜组溃疡面积缩小一半时间、快速尿素酶试验转阴时间、溃疡愈合时间和对照组比较有优势,P<0.05。药物内镜组和对照组再出血因素相似,P>0.05。结论四联方案+消化内镜治疗胃溃疡出血效果好。
Objective To investigate the clinical effect of digestive endoscopy combined with quadruple therapy in the treatment of gastric ulcer bleeding and the factors of re-bleeding.Methods 100 patients with gastric ulcer bleeding in our hospital from January 2017 to February 2018 were selected.The patients were randomly divided into four groups.The control group received quadruple therapy,while the drug endoscopy group received quadruple therapy plus digestive endoscopy.To compare the curative effect of gastric ulcer hemorrhage between two groups;Ulcer area reduced by half time,fast urease test negative time,ulcer healing time;Patients’symptom score before and after treatment;Re-bleeding factors.Results The drug endoscopy group had higher efficacy,P<0.05.The total effective rate in the drug endoscopy group was 100%.The total effective rate in the control group was 80%.Before treatment,the symptom scores of the control group and the drug endoscopy group were compared,P>0.05.After treatment,the symptom score of the drug endoscopy group changed more significantly,P<0.05.In the control group,the pre-treatment symptom score was(3.26±1.53)points,while the post-treatment symptom score was(1.67±0.67)points.The symptom score of the drug-endoscopic group was(3.24±1.56)points,while that of the post-treatment group was(0.51±0.21)points.Compared with the control group,the drug endoscopy group had an advantage in the reduction of ulcer area by half,the conversion time of fast urease test to negative,and the ulcer healing time,P<0.05.The factors of rebleeding in the endoscopic group and the control group were similar,P>0.05.Conclusion Quadruple therapy plus digestive endoscopy is effective in the treatment of gastric ulcer bleeding.
作者
陈昕
CHEN Xin(Fengcheng Central Hospital,Fengcheng 118100,China)
出处
《中国医药指南》
2020年第15期130-131,共2页
Guide of China Medicine
关键词
消化内镜
四联方案
胃溃疡出血
临床疗效
再出血因素
Digestive endoscopy
Quadruple regimen
Gastric ulcer bleeding
Clinical efficacy
Rebleeding factors
