摘要
脑出血具有高致残及高致死性特点,至今仍缺少有效的防治手段,因此迫切需要围绕脑出血临床救治面临的关键科学问题,从其发生发展的关键机制出发,开展基础临床转化研究,为脑出血防治提供新思路。既往关于脑出血发病机制的理论仍需进一步完善,利用现代基因测序及多组学的方法有望窥探脑出血发病机制的全貌。血肿形成和继发性脑损害是脑出血发展的重要环节,微创血肿清除术理应是未来脑出血治疗的首选方法,但仍需从治疗时间窗和治疗方式方面,并结合影像学等多学科开展创新临床研究。
Intracerebral hemorrhage(ICH)has features of high disability and high lethality,which is still lack for effective preventions and treatments.Therefore,it is urgent to focus on the key scientific problems facing the clinical treatment of ICH,and carry out basic clinical translational research from the key mechanism of occurrence and development,providing new ideas for ICH preventions and treatments.The previous theories about the pathogenesis of ICH are still need to be further explored.The use of modern gene sequencing and multi-omics methods is expected to reveal the whole picture of the pathogenesis of ICH.Hematoma formation and secondary brain damage are important to the development of ICH.Minimally invasive hematoma removal should be the first choice for ICH treatment in the future,but it is still necessary to push innovative clinical research from multiple disciplines such as treatment time window,treatment methods and radiography.
作者
张钦
杨清武
Zhang Qin;Yang Qingwu(Department of Neurology,Xinqiao Hospital,Army Medical University of Chinese PLA,Chongqing 400037,China)
出处
《中华脑血管病杂志（电子版）》
2020年第1期47-49,共3页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
关键词
脑出血
内皮细胞
微创术
Intracerebral hemorrhage
Endothelial cell
Minimal invasive surgery
