摘要
目的基于数据挖掘归纳总结中医药治疗恶性胸腔积液(MPE)内服处方的组方规律。方法在CNKI中检索2009年8月~2019年7月中医药治疗MPE的相关文献,筛选出其内服处方,使用“中医传承辅助系统”软件对处方中药物特性、频次及新方等进行挖掘与分析。结果筛选出治疗MPE的方剂共127首,药物共220味;四气五味中温性、甘味出现频次最多;常用药物是葶苈子、茯苓、大枣、桂枝、黄芪、白术;常用药对及组合共28组;聚类出新处方7个。结论MPE的治法包括温阳化饮、清热解毒、行气活血、益气行水。顾护脾胃是治疗MPE的重要思想。经方和黄芪辨证搭配使用是治疗MPE的核心。
Objective To conclude and summarize composing law of traditional Chinese medicine formulation for oral administration in treating malignant pleural effusion(MPE)based on data mining.Methods The related literatures of traditional Chinese medicine treating MPE from August 2009 to July 2019 were searched in CNKI.The internal prescriptions of literatures were screened.The medicinal properties,frequency of medication and new prescriptions of that internal prescriptions was sorted and analyzed by a software named“Chinese medicine inheritance support system”.Results One hundred and twenty-seven oral prescriptions treating MPE and 220 herbs were screened;the most frequent four nature and five flavour of drugs was wen and gan.“Semen Descurainiae”,“Poria”,“Fructus Jujubae”,“Ramulus Cinnamomi”,“Radix Astragali seu Hedysari”,“Rhizoma Atractylodis Macrocephalae”were more frequent used in herbs.A total of 28 commonly used herb pairs and combinations was found,7 new prescriptions were clustered.Conclusion Treatment of MPE includes warming yang for resolving fluid retention,clearing heat and removing toxicity,activating qi and promoting blood circulation,and benefiting qi and diuresis.Taking care of the spleen and stomach is an important idea for treating MPE.The core of MPE treatment is to combinate classical prescriptions and astragalus following syndrome differentiation.
作者
贾海女
张沂
周梦玲
吕明圣
高伟华
李文哲
晏军
JIA Hainü;ZHANG Yi;ZHOU Mengling;LYU Mingsheng;GAO Weihua;LI Wenzhe;YAN Jun(Department of Respiration,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Department of Encephalology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Department of Respiration,the Third Hospital of Beijing University of Chinese Medicine,Beijing 100191,China;Department of Nephropathy,the Third Hospital of Beijing University of Chinese Medicine,Beijing 100191,China;Department of Internal Medicine,Nankou Hospital of Changping District in Beijing City,Beijing 102202,China)
出处
《中国医药导报》
CAS
2020年第14期150-154,共5页
China Medical Herald
基金
国家自然科学基金资助项目(81373589)。
关键词
数据挖掘
恶性胸腔积液
组方规律
中医传承辅助系统
Data mining
Malignant pleural effusion
Prescription rule
Chinese medicine inheritance support system
