摘要
目的:研究先天性心脏病(CHD)患儿相关危险因素及营养风险筛查情况,为临床诊治CHD患儿提供理论参考。方法:选取2014年1月-2019年12月成都医学院附属第一医院收治的CHD患儿150例作为研究组,另取同期于该院接受体检的健康儿童150例作为对照组。分别对比两组研究对象父母的年龄、胎数、产检次数、烟草暴露情况、负性生活事件情况以及产妇营养不良情况,多因素Logistic回归分析CHD患儿相关危险因素;同时,采用营养风险筛查工具对两组研究对象进行营养风险筛查。结果:研究组患儿疾病分布占比从高到低的顺序分别为房间隔缺损(29.33%)、动脉导管未闭(24.67%)、室间隔缺损(20.67%)、法洛四联症(8.00%)以及房室间隔缺损(6.67%)。研究组父亲年龄≥50岁、母亲年龄≥35岁、多胞胎、产检次数<9次、烟草暴露、负性生活事件以及产妇营养不良人数占比均高于对照组(P<0.05)。经多因素Logistic回归分析可得,父亲年龄≥50岁、母亲年龄≥35岁、多胞胎、产检次数<9次以及烟草暴露均是CHD患儿的独立危险因素(P<0.05)。研究组患儿低度风险人数占比低于对照组,而重度风险人数占比高于对照组,差异有统计学意义(P<0.05),两组中度风险人数占比比较差异无统计学意义(P>0.05)。结论:CHD患儿的影响因素包括父亲年龄≥50岁、母亲年龄≥35岁、多胞胎、产检次数<9次以及烟草暴露,且患儿营养风险较高,值得临床重视。
Objective: To study the risk factors and nutritional risk screening of children with congenital heart disease(CHD), and to provide theoretical reference for clinical diagnosis and treatment of CHD. Methods: 150 children with CHD admitted to the First Affiliated Hospital of Chengdu Medical College from January 2014 to December 2019 were selected as the study group, and 150 healthy children who received physical examination in the hospital at the same time were selected as the control group. The age of parents, the number of foetus, Production inspection times, tobacco exposure, negative life events and maternal malnutrition of the two groups were compared, and the related risk factors of children with CHD were analyzed by multi factor Logistic regression. Meanwhile, the nutritional risk screening tool was used to screen the two groups of subjects. Results: The order of disease distribution in the study group was from high to low, which were atrial septal defect(29.33%), patent ductus arteriosus(24.67%), ventricular septal defect(20.67%), tetralogy of Fallot(8.00%) and atrioventricular septal defect(6.67%). Father’s age ≥50 years, mother’s age ≥35 years, multiple fetus, production inspection times<9 times, tobacco exposure, negative life events and maternal malnutrition ratio in study group was higher than that of control group(P<0.05). Multivariate Logistic regression analysis showed that father’s age ≥50 years, mother’s age≥35 years, multiple fetus, production inspection times<9 times and tobacco exposure were all independent risk factors of children with CHD(P<0.05). The proportion of children with low risk in the study group was lower than that of the control group, and the proportion of severe risk was higher than that of the control group, the difference were statistically significant(P<0.05). There was no significant difference in the comparison of the two groups of moderate risk(P>0.05). Conclusion: The influencing factors of children with CHD include father’s age ≥50 years, mother’s age ≥35 years, multiple fetus, production inspection times<9 times and tobacco exposure, and the children’s nutritional risk is high, which deserves clinical attention.
作者
陈丹丹
陈丹镝
鲁利群
冉凤萍
陈倩倩
李红梅
吕伟超
CHEN Dan-dan;CHEN Dan-di;LU Li-qun;RAN Feng-ping;CHEN Qian-qian;LI Hong-mei;LV Wei-chao(Department of Health Policy and Management,West China School of Public Health of Sichuan University/West China Fourth Hospital of Sichuan University,Chengdu,Sichuan,610041,China;Department of Medical Administration Division,the First Affiliated Hospital of Chengdu Medical College,Chengdu,Sichuan,610500,China;Department of Pediatrics,the First Affiliated Hospital of Chengdu Medical College,Chengdu,Sichuan,610500,China;Department of Obstetrics,the First Affiliated Hospital of Chengdu Medical College,Chengdu,Sichuan,610500,China;Health Management Center,the First Affiliated Hospital of Chengdu Medical College,Chengdu,Sichuan,610500,China)
出处
《现代生物医学进展》
CAS
2020年第8期1557-1560,1595,共5页
Progress in Modern Biomedicine
基金
四川省卫计委科研项目(2018JY0301)
关键词
先天性心脏病
患儿
危险因素
营养风险
筛查
Congenital heart disease
Children
Risk factors
Nutritional risk
Screening
