摘要
目的研究肝吸虫感染、乙肝病毒感染与肝癌关系。方法方便选择武鸣地区2017年8月—2019年8月期间收入的120例肝癌患者作为研究组,并选择同期该院收入的其他癌症患者120例作为对照组,观察两组患者肝吸虫、乙肝病毒感染发生率,HBV血清标志物阳性率。结果研究组肝吸虫感染12.50%%、乙肝病毒感染发生率85.00%均高于对照组3.33%、5.00%,差异有统计学意义(χ2=5.769、129.293,P=0.016、0.000)。两组患者在HBeAg阳性率上差异无统计学意义(χ2=0.052,P=0.819);其中研究组在HBsAg 70.83%、HBeAb 46.67%、HBcAb75.00%阳性率高于对照组6.67%、4.17%、8.33%,而在HBsAb上0.83%低于对照组30.00%,差异有统计学意义(χ2=86.720、47.638、91.439、32.629,P=0.000、0.000、0.000、0.000)。肝癌与肝吸虫感染、乙肝病毒感染之间为均正相关,其中存在肝吸虫感染、乙肝病毒感染患者,肝癌发生率也就越高,差异有统计学意义(r=0.058,P<0.05)。结论肝吸虫感染、乙肝病毒感染与肝癌的发生存在一定联系,对于合并出现肝吸虫感染、乙肝病毒感染患者,需要高度重视其肝癌发病情况,是肝癌的致病危险因素之一,对于这类患者需要及时进行治疗,避免病情出现恶化。
Objective To study the relationship between liver fluke infection,hepatitis B virus infection and liver cancer.Methods Convenient selection a total of 120 patients with liver cancer who received income from August 2017 to August 2019 in Wuming area were selected as the study group,and 120 patients with other cancers who were admitted to our hospital during the same period were selected as the control group.The two groups of patients were observed for liver fluke and hepatitis B virus Incidence rate,HBV serum marker positive rate.Results The incidence of liver fluke infection in the study group was 12.50%and the incidence of hepatitis B virus infection was 85.00%,which were higher than those in the control group by 3.33%and 5.00%.There was no difference in HBeAg positive rates between the two groups of patients statistically significant(χ2=0.052,P=0.819);the positive rates in the study group were 70.83%in HBsAg,46.67%in HBeAb,and 75.00%in HBcAb.8.33%,while 0.83%on HBsAb was lower than 30.00%in the control group,the difference was statistically significant(χ2=86.720,7.638,91.439,32.629,P=0.000,0.000,0.000,0.000).There was a positive correlation between liver cancer and liver fluke infection and hepatitis B virus infection.Among patients with liver fluke infection and hepatitis B virus infection,the incidence of liver cancer was higher,the difference was statistically significant(r=0.058,P<0.05).Conclusion Liver fluke infection and hepatitis B virus infection are related to the occurrence of liver cancer.For patients with liver fluke infection and hepatitis B virus infection,it is necessary to pay great attention to the incidence of liver cancer.It is one of the risk factors for liver cancer.It needs to be treated in time to avoid the deterioration of the condition.
作者
曾毅飞
吴江山
黄兴蔚
莫兰梅
方青华
ZENG Yi-fei;WU Jiang-shan;HUANG Xing-wei;MO Lan-mei;FANG Qing-hua(Department of Gastroenterology,Wuming Hospital,Guangxi Medical University,Nanning,Guangxi,530100 China)
出处
《中外医疗》
2020年第11期79-81,共3页
China & Foreign Medical Treatment
关键词
肝吸虫感染
乙肝病毒感染
肝癌
Liver fluke infection
Hepatitis B virus infection
Liver cancer
