摘要
目的:探讨普通型新型冠状病毒感染肺炎(COVID-19)患者肝损与消化道症状的关系。方法:选取湖北省鄂州市雷山医院住院治疗的225例确诊普通型COVID-19患者为研究对象,按肝功能异常与否分为肝功能异常组(n=48)和肝功能正常组(n=177),收集2组患者的临床资料并比较;按有无消化道症状分为消化道症状组(n=31)和无消化道症状组(n=194例),收集2组患者入院时的血清丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)及总胆红素(TBIL)数值并比较。结果:肝功能异常组患者的平均住院时间及消化道症状发生率均高于肝功能正常组,差异有统计学意义(P <0. 05);消化道症状组患者血清ALT和AST异常率均明显高于无消化道症状组,差异有高度统计学意义(P <0. 001)。结论:合并有消化道症状的普通型COVID-19患者较无消化道症状者,可能较易发生肝功能异常。
Objective:To explore the relationship between liver impairment and symptoms of digestive tract in patients with common COVID-19.Methods:225 patients who were admitted to Leishan Hospital of Ezhou City,Hubei Province were selected as the subjects of study,and they were divided into abnormal liver function group(n=48)and normal liver function group(n=177)according to whether the liver function was abnormal or not.Clinical data of 2 groups were collected and compared.The symptoms of digestive tract were divided into the group of digestive tract symptom(n=31)and the group of non-digital tract symptom(n=194).The values of serum alanine aminotransferase(ALT),aspartate aminotransferase(AST)and total bilirubin(TBIL)were collected and compared in two groups at admission.Results:The average length of hospital stay and the incidence of digestive tract symptoms in patients with abnormal liver function group were higher than those in normal liver function group,and the difference was statistically significant(P<0.05).The abnormal rate of serum ALT and AST in patients with group of digestive tract symptom was significantly higher than that in patients without group of digestive tract symptom,and the difference was highly statistically significant(P<0.001).Conclusion:Common COVID-19 patients with symptom of digestive tract are more likely to have abnormal liver function than those without gastrointestinal symptoms.
作者
李永宁
左石
李昆
喻超
LI Yongning;ZUO Shi;LI Kun;YU Chao(The Affiliated Hospital of Guizhou Medical University,Guiyang 550004,Guizhou,China)
出处
《贵州医科大学学报》
CAS
2020年第6期733-736,741,共5页
Journal of Guizhou Medical University
关键词
肺炎
病毒性
新型冠状病毒
新型冠状病毒肺炎
血管紧张素转换酶Ⅱ
肝功能异常
消化道症状
pneumonia
viral
novel coronavirus
corona virus disease 2019(COVID-19)
angiotensin converting enzymeⅡ(ACEⅡ)
abnormal liver function
symptom of digestive tract
