摘要
目的分析非进食障碍肥胖人群在爱荷华州赌博任务(IGT)中的决策情况。方法计算机检索万方中文科技期刊数据库、中国知网、Pubmed、Web of Science、Elsevier ScienceDirect数据库中所有关于IGT测量非进食障碍肥胖者决策的随机对照试验,检索年限为数据库建库至2019年7月,语种为中、英文。由两位研究者按照制定的纳入与排除标准和Jadad质量评分表独立筛选、评估文献,提取数据。用RevMan 5.3软件进行Meta分析。结果共有9篇文献符合要求纳入研究。Meta分析结果显示,非进食障碍肥胖组IGT总净得分明显低于健康对照组,差异具有统计学意义(MD=-12.28,95%CI=-15.52^-9.04,P<0.001)。IGT中的Block1结果显示,两组间任务表现差异无统计学意义(MD=0.26,95%CI=-0.68~1.20,P>0.05);Block2~5结果显示,非进食障碍肥胖组IGT得分明显低于健康对照组,差异具有统计学意义(Block2:MD=-2.93,95%CI=-4.39^-1.47,P<0.001;Block3:MD=-2.94,95%CI=-4.44^-1.45,P<0.001;Block4:MD=-3.45,95%CI=-4.80^-2.10,P<0.001;Block5:MD=-3.59,95%CI=-5.60^-1.58,P<0.001)。结论非进食障碍肥胖人群的决策能力明显受损。
Objective To investigate the decision-making ability of obese individuals without eating disorders in Iowa Gambling Task(IGT).Methods Wanfang Data,CNKI,PubMed,Web of Science,and Elsevier ScienceDirect were searched for randomized controlled trials(RCTs)on IGT for evaluating the decision-making ability in obese individuals without eating disorders published up to July 2019 and written in English or Chinese.Two researchers independently performed literature screening,assessment,and data extraction according to the inclusion and exclusion criteria and the Jadad quality scale,and RevMan 5.3 was used to perform the Meta-analysis.Results A total of 9 RCTs which met the requirements were included in the study.The Meta-analysis showed that the non-eating disorder obese group had a significantly lower total net score of IGT than the healthy control group(mean difference(MD)=-12.28,95%confidence interval(CI)=-15.52 to-9.04,P<0.001).The results of Block1 in IGT showed that there was no significant difference in task performance between the two groups(MD=0.26,95%CI=-0.68 to 1.20,P>0.05),and the results of Block2-5 showed that the non-eating disorder obese group had a significantly lower IGT score than the healthy control group(Block2:MD=-2.93,95%CI=-4.39 to-1.47,P<0.001;Block3:MD=-2.94,95%CI=-4.44 to-1.45,P<0.001;Block4:MD=-3.45,95%CI=-4.80 to-2.10,P<0.001;Block5:MD=-3.59,95%CI=-5.60 to-1.58,P<0.001).Conclusion Impaired decision-making ability is observed in obese individuals without eating disorders.
作者
李亚铃
鲁玉洁
谭巧文
王志宏
郭宗君
LI Yaling;LU Yujie;TAN Qiaowen;WANG Zhihong;GUO Zongjun(Department of Geriatrics, The Affiliated Hospital of Qingdao University, Qingdao 266003, China)
出处
《青岛大学学报（医学版）》
CAS
2020年第3期313-317,共5页
Journal of Qingdao University(Medical Sciences)
基金
山东省科技发展计划项目(2011YD18045)
山东省自然科学基金资助项目(ZR2012HM049)
青岛市科技局科研基金资助项目(09-1-1-33-nsh,15-9-2-74-nsh)
青岛市黄岛区科技局科研基金资助项目(2014-1-73)。
关键词
肥胖症
决策
META分析
obesity
decision making
Meta-analysis
