摘要
目的应用超声评价红花注射液经眼部皮肤离子导入治疗后眼部动脉血流动力学变化情况。方法选取我院体检健康者40例,共80只眼,右眼均用面纱浸湿红花注射液20 ml,覆盖右眼部皮肤(治疗组);左眼均用面纱浸湿生理盐水20 ml,覆盖左眼部皮肤(对照组),两组同时采用离子导入仪治疗20 min。应用彩色多普勒超声检测两组治疗前后视网膜中央动脉、睫状动脉、眼动脉的收缩期峰值流速(PSV)、舒张末期流速(EDV)及阻力指数(RI),并对比分析。结果治疗组经红花注射液离子导入治疗后视网膜中央动脉、睫状动脉、眼动脉的PSV和EDV分别为(14.93±2.36)cm/s和(4.81±1.03)cm/s、(14.74±2.64)cm/s和(5.36±1.10)cm/s、(35.91±6.71)cm/s和(8.13±2.36)cm/s,PSV与EDV差值亦增加,与治疗前比较差异均有统计学意义(均P<0.05);仅RI治疗前后比较差异无统计学意义。对照组视网膜中央动脉、睫状动脉、眼动脉各参数治疗前后比较差异均无统计学意义。结论中药制剂红花注射液经眼部皮肤离子导入治疗可改善眼部动脉血供;彩色多普勒超声能够为该方法治疗眼部疾病提供客观的血流动力学依据。
Objective To evaluate the ophthalmic artery hemodynamic changes induced by safflower injection iontophoresed through ocular skin by color Doppler ultrasound.Methods Forty healthy subjects(80 eyes)in our hospital were involved in this reseach.The right eyes were covered with a veil soaked with 20 ml safflower injection(treatment group),the left eyes were covered with a veil soaked with 20 ml normal saline(control group).The two groups were treated with iontophoresis at the same time for 20 min.The changes of the PSV,EDV and RI of CRA,PCA and OA in two groups were detected by color Doppler ultrasound and comparative analysis were made.Results After safflower injection was applied through ocular skin iontophoresis,the PSV and EDV of CRA,PCA and OA of the right eyes were(14.93±2.36)cm/s and(4.81±1.03)cm/s,(14.74±2.64)cm/s and(5.36±1.10)cm/s,(35.91±6.71)cm/s and(8.13±2.36)cm/s,PSV-EDV was increased,there were significantly differences before and after safflower injection iontophoresis(all P<0.05).There was no significant difference of resistanc index between the two groups.For the left eyes,there was no significant hemodynamic changes before and after the treatment.Conclusion Safflower injection through ocular skin iontophoresis leads to significant changes in ophthalmic artery hemodynamics.The color Doppler ultrasound could provide the quantitative evaluation information for the treatment of safflower injection through ocular skin iontophoresis.
作者
刘可
邢静
李慧丽
谢昭鹏
LIU Ke;XING Jing;LI Huili;XIE Zhaopeng(Department of Ultrasound,Chongqing Traditional Chinese Medicine Hospital,No.4 Clinical Medicine School of Chengdu University of TCM,Chongqing 400021,China)
出处
《临床超声医学杂志》
CSCD
2020年第6期469-471,共3页
Journal of Clinical Ultrasound in Medicine
基金
重庆市卫生和计生委中医药科技项目(ZY201703003)
成都中医药大学医院专项课题(YYZX20180048)。
关键词
超声检查
多普勒
彩色
红花注射液
离子导入
眼动脉
Ultrasonography
Doppler
color
Safflower injection
Iontophoresis
Ophthalmic artery
