摘要
目的:评价与分析医院Ⅰ类切口手术患者围手术期预防使用抗菌药物的合理性,为规范围手术期抗菌药物的预防使用提供参考。方法:抽取医院2019年4月—6月间收治的Ⅰ类切口手术患者1126例临床资料,分析其围手术期预防使用抗菌药物的合理性。结果:1126例Ⅰ类切口手术患者中,围术期预防用抗菌药物302例的比例占26.82%;大部分清洁手术预防用抗菌药物的选用以第3代头孢菌素为主;302例清洁手术预防用药时机不合理主要表现在术前≥1 h的19例(占6.30%),术前未用术后用药的6例(占1.99%);预防用药维持时间超过24 h的111例(占36.75%);预防用药合理的仅为11.59%;不合理用药类型主要为药物选用不适宜、给药时机不正确、无指征用药及疗程不适宜等。结论:医院Ⅰ类切口手术围手术期预防用抗菌药物在药物品种选择及给药疗程方面仍存在不合理现象,尚待进一步规范。
Objective:To evaluate and analyze the rationality of prophylactic medication of antibiotics in perioperative period for patients with typeⅠincision surgery in hospitals,so as to provide reference for the prophylactic use of antibiotics in perioperative period.Methods:The clinical data of 1126 patients with typeⅠincision surgery admitted to the hospital from April to June 2019 were extracted to analyze the rationality of prophylactic use of antibiotics during perioperative period.Results:Among the 1126 patients with typeⅠincision surgery,the proportion of perioperative prophylactic use of antimicrobial agents in 302 patients accounted for 26.82%.The third generation cephalosporin was the main antibacterial agents for the prevention of clean surgery.In 302 cases,the unreasonable timing of prophylactic medication for clean surgery was mainly manifested in 19 cases(6.30%)that were greater than or equal to 1 hour before surgery,and 6 cases(1.99%)who did not use before surgery.The duration of prophylactic medication was longer than 24 hours,accounting for 36.75%of the 111 cases.Only 11.59%of the patients were rational in preventive drug use.The types of unreasonable drug use mainly include inappropriate drug selection,incorrect timing of drug administration,inappropriate drug requisition without indication and inappropriate course of treatment.Conclusion:The perioperative preventive medication for typeⅠincision surgery in our hospital still has unreasonable phenomena in the selection of drugs and the course of administration.It should be further standardized.
作者
虞佳
罗美凤
YU Jia;LUO Mei-feng(Department of Pharmacy,The No.3 Hospital Affiliated to Nanchang University,Nanchang 330008,China)
出处
《抗感染药学》
2020年第5期671-675,共5页
Anti-infection Pharmacy
关键词
Ⅰ类切口手术
围手术期
抗菌药物
预防用药
合理性
type 1 incision surgery
perioperative period
antibacterial drugs
prophylactic medication
rationality
