摘要
目的:观察曲美他嗪联合经皮冠状动脉介入术(PCI)对心肌梗死患者心肌梗死溶栓试验(TIMI)血流分级及预后的影响。方法:选择2017年7月-2019年6月笔者所在医院治疗的心肌梗死患者82例,按随机数字表法分为两组,均41例。对照组接受PCI治疗,观察组则加用曲美他嗪治疗。比较两组TIMI血流分级、左心射血分数(LVEF)及并发症。结果:治疗前两组TIMI血流分级、LVEF对比,差异无统计学意义(P>0.05);治疗后观察组TIMI血流分级0级、1级、2级、3级分别为0、12.20%、24.39%、63.41%,LVEF(60.34±7.21)%,优于对照组的4.88%、17.07%、36.59%、41.46%、(53.75±5.14)%,差异有统计学意义(P<0.05);观察组并发症发生率(7.32%)低于对照组(24.40%),差异有统计学意义(P<0.05)。结论:心肌梗死患者接受曲美他嗪、PCI联合治疗安全可行,有利于改善梗死动脉血流灌注,保护心肌,改善心功能,且并发症较少。
Objective:To observe the effect of Trimetazidine combined with percutaneous coronary intervention (PCI) on blood flow classification and prognosis of myocardial infarction thrombolysis test (TIMI) in patients with myocardial infarction.Method:Eighty-two patients with myocardial infarction treated in our hospital from July 2017 to June 2019 were selected and divided into two groups according to the random number table method,with 41 cases each.The control group received PCI,while the observation group was treated with Trimetazidine on the basis of the control group.The TIMI blood flow grade,left ventricular ejection fraction (LVEF),and complications were compared between the two groups.Result:There were no significant difference in the TIMI blood flow grade and LVEF between the two groups before treatment (P>0.05).After treatment,the TIMI blood flow grade (grade 0,grade 1,grade 2,grade 3) were 0,12.20%,24.39%,63.41%,LVEF was (60.34±7.21)% in the observation group,they were better than 4.88%,17.07%,36.59%,41.46%,(53.75±5.14)% in the control group,the differences were statistically significant (P<0.05).The incidence of complications in the observation group (7.32%) was lower than that in the control group (24.40%),and the difference was statistically significant (P<0.05).Conclusion:Patients with myocardial infarction can receive Trimetazidine and PCI in combination.It is safe and feasible,and it is beneficial to improve infarct arterial blood perfusion,protect myocardium,improve cardiac function,and has fewer complications.
作者
陈子凌
CHEN Ziling(Fuzhou Second Hospital Affiliated to Xiamen University,Fuzhou 350000,China)
出处
《中外医学研究》
2020年第14期44-46,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
心肌梗死
曲美他嗪
经皮冠状动脉介入术
TIMI血流分级
心功能
并发症
Myocardial infarction
Trimetazidine
Percutaneous coronary intervention
TIMI blood flow classification
Cardiac function
Complications
