摘要
目的:探讨体重管理对超重和肥胖的糖耐量减低(IGT)患者转归的影响。方法:选取2018年4-8月体检中新诊断为IGT的282例超重和肥胖患者作为研究对象,按照年龄和性别相匹配的原则将其中150例分配到管理组,132例作为对照组。对照组接受常规教育,管理组接受为期1年的以生活方式干预为措施的体重管理,1年后对两组体重、血糖和转归情况进行比较。结果:1年后管理组BMI、2 h PBG和HbA1c均低于对照组及入组时,差异均有统计学意义(P<0.05),FPG与入组时及对照组比较差异无统计学意义(P>0.05);对照组2 h PBG和HbA1c均高于入组时,差异均有统计学意义(P<0.05),BMI和FPG与入组时比较差异无统计学意义(P>0.05)。1年后两组进展为糖尿病患者比例差异无统计学意义(P>0.05),管理组糖耐量减低患者比例低于对照组,糖耐量正常患者比例高于对照组,差异均有统计学意义(P<0.05)。结论:以生活方式干预为措施的体重管理能够部分逆转超重和肥胖的IGT患者的糖耐量减低状态。
Objective:To explore the effect of weight management on overweight and obese patients with impaired glucose tolerance(IGT).Method:From April to August 2018,282 overweight and obese patients with newly diagnosed IGT were selected as subjects,according to the principle of age and sex matching,150 cases of them were assigned to the management group and 132 cases as the control group.The control group received regular education,and the management group received a one-year weight management with lifestyle intervention.After one year,the weight,blood sugar and outcome of the two groups were compared.Result:One year later,the BMI,2 h PBG and HbA1c of the management group were lower than those of the control group and when entering the group(P<0.05),there was no significant difference in FPG compared with the control group and when entering the group(P>0.05).The 2 h PBG and HbA1c in the control group were higher than those when entering the group(P<0.05),there was no significant difference in BMI and FPG compared with when entering the group(P>0.05).After 1 year,there was no significant difference in the proportion of diabetic patients(P>0.05),the proportion of patients with decreased glucose tolerance in the management group was lower than that in the control group,the proportion of patients with normal glucose tolerance was higher than that in the control group,the differences were statistically significant(P<0.05).Conclusion:Weight management with lifestyle interventions can partially reverse glucose tolerance status in overweight and obese IGT patients.
作者
郭丽萍
GUO Liping(Aerospace Center Hospital,Beijing 100049,China)
出处
《中外医学研究》
2020年第15期173-175,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
体重管理
超重和肥胖
糖耐量减低
Weight management
Overweight and obese
Impaired glucose tolerance
