摘要
目的探讨去骨瓣减压术联合乌司他丁注射液对重型颅脑损伤患者的应用效果。方法选择2016年3月至2019年1月在某院接受治疗的90例重型颅脑损伤患者,根据治疗方法不同分为两组,各45例。对照组实施去骨瓣减压术联合吡拉西坦注射液治疗,观察组实施去骨瓣减压术联合乌司他丁注射液治疗,对比两组血流动力学指标及神经功能水平变化情况。结果观察组最小血流速度(Vmin)(13.11±2.22)cm/s、最大血流速度(Vmax)(44.26±5.89)cm/s、平均血流量(Qmean)(12.21±3.65)mL/s均高于对照组的(9.20±1.76)cm/s、(39.02±5.11)cm/s、(9.74±2.33)mL/s,脑血管阻力(R)(1.35±0.12)mPA/(s·m)值低于对照组的(1.60±0.13)mPA/(s·m),差异有统计学意义(P<0.05);观察组美国国立卫生研究院卒中量表(NIHSS)评分(21.30±2.82)分低于对照组的(25.30±3.74)分,差异有统计学意义(P<0.05)。结论去骨瓣减压术联合乌司他丁注射液治疗,可有效改善重型颅脑损伤患者的脑部血供状况,促进神经功能恢复。
Objective To explore the application effects of bone flap decompression combined with Ulinastatin injection on patients with severe craniocerebral injury.Methods A total of 90 patients with severe craniocerebral injury who received treatment in a hospital from March 2016 to January 2019 were selected and divided into two groups according to different treatment methods,with 45 patients in each group.The control group was treated with bone flap decompression combined with Piracetam injection,and the observation group was treated with bone flap decompression combined with Ulinastatin injection.The changes of hemodynamic indexes and neurological function level in the two groups were compared.Results The minimum blood flow velocity(Vmin)(13.11±2.22)cm/s,maximum blood flow velocity(Vmax)(44.26±5.89)cm/s,mean blood flow(Qmean)(12.21±3.65)mL/s of the observation group were all higher than those of the control group(9.20±1.76)cm/s,(39.02±5.11)cm/s,and(9.74±2.33)mL/s.Cerebral vascular resistance(R)value(1.35±0.12)mPA/(s·m)was lower than the control group(1.60±0.13)mPA/(s·m),the difference was statistically significant(P<0.05).The NIHSS score of the observation group(21.30±2.82)was lower than that of the control group(25.30±3.74),and the difference was statistically significant(P<0.05).Conclusion Bone flap Decompression combined with Ulinastatin injection can effectively improve the cerebral blood supply in patients with severe craniocerebral injury and promote the recovery of neurological function.
出处
《中国疗养医学》
2020年第7期773-775,共3页
Chinese Journal of Convalescent Medicine
关键词
重型颅脑损伤
去骨瓣减压术
乌司他丁注射液
Severe craniocerebral injury
Bone flap decompression
Ulinastatin injection
