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皮肤电导作为癫痫全面性强直-阵挛发作报警指标的可行性研究 被引量:1

The feasibility study of electrodermal activity as an alarm index for generalized tonic-clonic seizure
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摘要 目的观察癫痫发作时皮肤电导(EDA)的变化与全面性强直-阵挛发作(GTCs)的匹配性。方法采用Empatica E4传感器收集EDA、肢体运动等多项外周参数,选取每周均有GTCs发作的成年癫痫患者手腕佩戴E4腕表设备时同步进行24 h视频EEG(VEEG)监测。结果 61例成年癫痫患者接受24 h VEEG检查,共监测到9次GTCs发作,均有EDA升高。与无GTCs发作组相比差异有统计学意义(P<0.001)。监测到30次部分性发作,EDA无明显变化。肢体运动增快可见于多种发作类型,差异无统计学意义(P>0.05)。结论 EDA与GTCs发作有高度一致性,可作为对GTCs发作报警的可穿戴设备重要参数之一。 Objective To observe the compatibility of electrodermal activity(EDA)'s changes with generalized tonic-clonic seizure(GTCs).Methods Empatica E4 sensor was used to collect EDA,limbs'movement and other peripheral parameters.Adult epilepsy patients with weekly frequency of GTCs were monitored by 24 h video EEG(VEEG)while wearing E4 wrist watch device on their wrist.Results Sixty-one adult patients with epilepsy were admitted for 24 h VEEG monitoring.A total of nine GTCs were detected,both of them had high EDA.Compared with the group without GTCs,the difference was statistically significant(P<0.001).Thirty partial seizures were monitored without significant change of EDA.Types of seizure had increased limbs'movement,which had no statistically significant difference between them(P>0.05).Conclusion EDA has a high consistency with GTCs,which can be used as one of the important parameters of wearable device to alarm GTCs.
作者 尚丽 王开颜 余爽 SHANG Li;WANG Kai-yan;YU Shuang(Department of Epilepsy Center,Deji Hospital,the Ninth Clinical Hospital of Qingdao University,Shanghai 200331,China)
出处 《临床神经病学杂志》 CAS 2020年第3期201-204,共4页 Journal of Clinical Neurology
基金 医工结合专项科研基金(Y854061405)。
关键词 皮肤电导 全面性强直-阵挛发作 癫痫 可穿戴设备 electrodermal activity generalized tonic-clonic seizures epilepsy wearable device
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