摘要
目的:探讨体外冲击波碎石术结合坦索罗辛对肾结石患者结石清除率及不良反应的影响。方法:按照随机数表法将2018年7月~2019年12月某院收治的100例肾结石患者分为对照组和观察组,各50例。两组均进行体外冲击波碎石术,对照组术后服用索利那新,观察组术后服用坦索罗辛,比较两组患者治疗2周后结石清除率及治疗期间不良反应、炎症指标。结果:观察组结石清除率高于对照组,PCT、TNF-α及CRP水平低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率相比,差异无统计学意义(P>0.05)。结论:体外冲击波碎石术结合坦索罗辛治疗肾结石可抑制炎性因子释放,有效减轻患者痛苦,促进结石排出,且安全性较强,值得推广。
Objective:To investigate the effect of extracorporeal shock wave lithotripsy combined with tamsulosin on stone clearance and adverse reactions in patients with kidney stones.Methods:According to the random number table method,100 cases of patients with kidney stones treated in a hospital from July 2018 to December 2019 were divided into control group and observation group,with 50 cases in each group.Both groups underwent extracorporeal shock wave lithotripsy.The control group was treated with solifenacin after surgery,and the observation group was treated with tamsulosin after surgery.The stone clearance rate,adverse reactions,and inflammation indicators after 2 weeks of treatment were compared between the two groups.Results:The stone removal rate in the observation group was higher than that in the control group,and the levels of PCT,TNF-α,and CRP were lower than those in the control group.The difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Extracorporeal shock wave lithotripsy combined with tamsulosin in the treatment of kidney stones can inhibit the release of inflammatory factors,effectively alleviate the patient's pain,promote the excretion of stones,which is relatively safe and worthy of promotion.
作者
周欢
雷志培
周晓帆
陈结能
容伟超
Zhou Huan;Lei Zhipei;Zhou Xiaofan;Chen Jieneng;Rong Weichao(Taishan City People's Hospital,Taishan 529200)
出处
《数理医药学杂志》
2020年第7期1025-1027,共3页
Journal of Mathematical Medicine
关键词
肾结石
体外冲击波碎石术
坦索罗辛
结石清除率
不良反应
kidney stones
extracorporeal shock wave lithotripsy
tamsulosin
stone clearance
adverse reactions
