摘要
正电子发射计算机体层摄影-CT(PET-CT)扫描可对潜伏性结核感染/亚临床结核病进行早期评估,确定潜在的感染病变部位;有助于不明原因发热患者寻找病因;通过观察病变处18F标记的氟代脱氧葡萄糖(18F-FDG)摄取情况了解病变的炎症反应,可对结核活动性做出客观评价。在抗结核治疗过程中,通过观察病变的18F-FDG摄取的系列变化可对治疗是否成功做出预测。但由于其价格昂贵等问题,目前该技术尚不具备临床广泛应用的条件;不过基于其技术优势,有望在结核病临床与基础研究中发挥作用。
Positron emission computed tomography-CT(PET-CT)scan can be used for evaluating the latent tuberculosis(TB)infection/subclinical TB infection in early stage,identifying the potential infectious lesions,finding the etiological factors in patients with unexplained fever,comprehending the inflammatory reaction of lesions by observing the uptake of fluorodeoxyglucose(18 F-FDG),and making an objective evaluation of TB activity.During the course of anti-TB treatment,the success of the treatment can be predicted by observing the series of changes of 18-FDG uptake of the lesion.However,due to the high price and other issues,the widespread clinical application of PET-CT is limited.Nevertheless,based on the technical advantages of PET-CT,it is still expected to play an important role in clinical and scientific research of TB.
作者
宋其生
路希维
SONG Qi-sheng;LU Xi-wei(Dalian Tuberculosis Hospital,Dalian 116033,China)
出处
《中国防痨杂志》
CAS
CSCD
2020年第6期621-625,共5页
Chinese Journal of Antituberculosis