摘要
目的:观察短波理疗仪治疗红斑毛细血管扩张型玫瑰痤疮(ETR)的临床疗效。方法:收集70例ETR患者,随机分为2组,其中治疗组40例,对照组30例。2组均每日早晚使用保湿霜,治疗组每隔1周进行1次短波理疗,疗程8周。治疗前、后由皮肤科医生盲态下对患者面部红斑及毛细血管扩张进行评分;患者对阵发性潮红、灼热及干燥症状进行评分。评分标准采用玫瑰痤疮4级评分。皮肤检测仪检测2组治疗前、后皮肤含水量和经皮水流失(TEWL)值。记录疗程中的不良反应。结果:治疗后治疗组患者面部红斑、灼热及干燥程度评分均较治疗前明显改善(P<0.05),治疗组改善优于对照组(P<0.05);对照组患者灼热及干燥程度评分均较治疗前明显改善(P<0.05)。2组毛细血管扩张评分及阵发性潮红评分比较,差异均无统计学意义(P>0.05)。治疗后2组患者皮肤含水量均增加,治疗组增加大于对照组(P<0.05);2组TEWL值均下降,治疗组下降大于对照组(P<0.05)。所有患者均无明显不良反应。结论:短波理疗仪治疗可明显改善ETR患者面部红斑、灼热及干燥症状,且安全性较好。
Objective:To evaluate the efficacy of short-wave therapy in patients with erythematotelangiectatic rosacea.Methods:Seventy patients with erythematotelangiectatic rosacea were randomized selected into treatment group(n=40)and control group(n=30).The treatment group underwent short-wave therapy every other week and received moisturizer twice a day for a 8-week period.The control group applied the same moisturizer twice a day only for a 8-week period.Clinical improvements in erythema and telangiectasia were scored by a dermatologist through blinded evaluation before and after the treatment.Patients were instructed to evaluate their disease symptoms including flushing,burning and dryness as well.Skin hydration and transepidermal water loss(TEWL)were measured and recorded before and after the treatment.Adverse reaction during the treatments were also documented.Results:Short-wave therapy resulted in improvements from baseline in erythema,burning and dryness in treatment groups(P<0.05).The treatment group significantly outperformed the control group on those scores(P<0.05).After the treatment,the scores of burning and dryness in the control group were significantly improved(P<0.05).Telangiectasia and flushing did not show significant improvements from baseline(P>0.05)in both treatment and control groups after the treatment.Levels of skin hydration increased and TEWL decreased significantly in both groups(P<0.05),and the treatment group had better improvements than the control group(P<0.05).No adverse reaction was observed throughout the study.Conclusions:Short-wave therapy is safe,effective and well-tolerated in the management of erythematotelangiectatic rosacea.It improves the symptoms of facial erythema,burning and dryness in patients with erythematotelangiectatic rosacea.
作者
许凌晖
许天星
郑月恋
郭燕妮
XU Ling-hui;XU Tian-xing;ZHENG Yue-lian;GUO Yan-ni(Department of Dermatology,the Second Affiliated Hospital of Fujian Medical University,Quanzhou 362000,China)
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2020年第6期370-373,共4页
Journal of Clinical Dermatology
基金
福建省临床重点专科建设项目(闽卫医政函[2017]739号)
福建省自然科学基金(2019J01467)资助项目。
