摘要
目的:研究帕金森病伴动脉粥样硬化老年患者给予辛伐他汀联合美多巴的临床效果。方法:本次研究选取的研究对象为帕金森病伴动脉粥样硬化老年患者60例,简单随机分为两组,30例患者为一组。对照组实施美多巴治疗,观察组采用辛伐他汀联合美多巴治疗。对比两组帕金森病伴动脉粥样硬化老年患者的临床总有效率、Webster评分、UPDRS评分以及不良反应发生率。结果:观察组帕金森病伴动脉粥样硬化老年患者的临床总有效率、Webster评分、UPDRS评分以及不良反应发生率均优于对照组,差异有统计学意义(P<0.05)。结论:联合应用美多巴和辛伐他汀治疗帕金森病伴动脉粥样硬化老年患者安全有效。
Objective To study the clinical effect of simvastatin combined with methadopa in elderly patients with Parkinson’s disease and atherosclerosis.Method 60 elderly patients with Parkinson’s disease and atherosclerosis who were treated in our hospital were selected and randomly divided into two groups,30 patients in one group.Madopa treatment(control group)and simvastatin combined with Madopa treatment(observation group).The clinical total effective rate,Webster score,UPDRS score and the incidence of adverse reactions were compared between the two groups.Results The total effective rate,Webster score,UPDRS score and adverse reaction rate of the elderly patients with Parkinson’s disease and atherosclerosis in the observation group were better than those in the control group(P<0.05).Conclusion The combination of Madopar and simvastatin is safe and effective in the treatment of elderly patients with Parkinson’s disease and atherosclerosis.
作者
张磊
ZHANG Lei(Neurology Department,Second Affiliated Hospital of University Of South China,Hengyang 421001,China)
出处
《吉林医学》
CAS
2020年第7期1580-1581,共2页
Jilin Medical Journal
