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妊娠合并视神经脊髓炎疾病的临床分析 被引量:1

Clinical Analysis of Pregnancy Complicated with Neuromyelitis Optica Spectrum Disorder
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摘要 目的通过病例分析及文献回顾,总结妊娠合并视神经脊髓炎谱系疾病的临床特点,产科相关风险,以及治疗方案。让产科医师熟知并了解该病,能为妊娠患者提供恰当的建议及孕期保健。方法回顾性分析某院2017年1月至2018年12月收治的5例妊娠合并视神经脊髓炎谱系疾病的临床资料,结合文献分析,探讨该病的临床特点,产科风险及治疗方案。结果妊娠合并视神经脊髓炎谱系疾病主要发病于育龄女性,平均(26.6±4.0)岁,母婴预后区别较大。本组5例妊娠合并视神经脊髓炎谱系疾病患者,均为育龄女性,缺乏孕前咨询及指导,孕期出现流产、早产等妊娠结局。结论视神经脊髓炎谱系疾病不是妊娠及继续妊娠的禁忌症,但患者往往缺乏相关的孕前及孕期教育。孕前需充分咨询及风险评估,及时诊断及治疗,严密监测病情变化,选择适当的妊娠时机及终止妊娠时机,产后及时评估病情及治疗,是改善母婴结局的关键。 Objective To summarize the clinical characteristics of the pregnancy with neuromyelitis optica spectrum disorder,as well as obstetric related risks,and treatment options through the case analysis and literature review.And,to provide suggestion for patients with pregnancy and prenatal care.Methods The clinical data of 5 cases of pregnancy complicated neuromyelitis optica spectrum disorder treated and terminated pregnancies in a hospital between January2011 and December 2018.The clinical manifestations,laboratory tests,treatment methods and prognosis of these patients were analyzed.Results Pregnancy with neuromyelitis optica speltrum disorder mainly occurs in women of childbearing age,with an average(26.6±4.0) years of age,with a large difference in maternal and infant prognosis.In this group,5 cases of pregnancy complicated with neuromyelitis optica speltrum disorder were all women of childbearing age.Conclusion Neuromyelitis optica speltrum disorder is not a contraindication to pregnancy and continued pregnancy,but patients often lack relevant pre-pregnancy and pregnancy education.Patients of pregnancy complicated with neuromyelitis optica spectrum disorder can have better maternal and fetal outcomes through timely diagnosis and treatment,dynamic monitoring,and timely pregnancy termination.
作者 张清泉 王世军 Zhang Qingquan;Wang Shijun(Department of gynaecology and obstetrics,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)
出处 《中国病案》 2020年第4期102-105,共4页 Chinese Medical Record
关键词 妊娠 临床特点 视神经脊髓炎谱系疾病 Pregnancy Clinical features Neuromyelitis optica spectrum disorder
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