摘要
目的观察针刺配合中医五行音乐疗法治疗非小细胞肺癌(NSCLC)化疗后轻、中度抑郁的临床疗效及对生活质量的影响。方法将151例NSCLC化疗后轻、中度抑郁患者随机分为治疗组76例和对照组75例。治疗组采用针刺配合中医五行音乐疗法治疗,对照组采用口服甘麦大枣汤配合中医五行音乐疗法治疗。观察两组治疗前后中医证候评分、匹兹堡睡眠质量指数(PSQI)评分、健康调查简表(SF-36)各项评分及副反应量表(TESS)评分的变化情况,并比较两组临床疗效。结果治疗组总有效率为85.5%,对照组为72.0%,两组比较差异具有统计学意义(P<0.05)。两组治疗后中医证候评分、PSQI评分、TESS评分及SF-36各项评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后中医证候评分、PSQI评分、TESS评分及SF-36中社会功能、情感职能、精神健康评分与对照组比较,差异均具有统计学意义(P<0.05)。结论针刺配合中医五行音乐疗法治疗NSCLC化疗后轻、中度抑郁疗效确切,能改善患者抑郁状态,提高其生活质量及睡眠质量。
Objective To observe the clinical efficacy of acupuncture plus five-element music therapy of Chinese medicine in treating mild-to-moderate depression after chemotherapy for non-small cell lung cancer(NSCLC)and its effect on the quality of life(QOL).Method A total of 151 NSCLC patients with mild-to-moderate depression after chemotherapy were randomized into a treatment group of 76 cases and a control group of 75 cases.The treatment group was intervened by acupuncture plus five-element music therapy of Chinese medicine,and the control group was treated with oral administration of Gan Mai Da Zao decoction plus five-element music therapy of Chinese medicine.The Chinese medicine syndrome and symptom score,Pittsburgh Sleep Quality Index(PSQI)score,36-item Short-form Health Survey(SF-36)score and Treatment Emergent Symptom Scale(TESS)score were observed before and after treatment in the two groups.The clinical efficacy was also compared between the two groups.Result The total effective rate was 85.5%in the treatment group versus 72.0%in the control group,and the between-group difference was statistically significant(P<0.05).The Chinese medicine syndrome and symptom score,PSQI score,TESS score and SF-36 component scores changed significantly after treatment in both groups(P<0.05).After treatment,the treatment group was significantly different from the control group comparing the Chinese medicine syndrome and symptom score,PSQI score,TESS score,and the scores of social function,affective role and mental health of SF-36(P<0.05).Conclusion Acupuncture plus five-element music therapy of Chinese medicine is effective in treating mild-to-moderate depression after chemotherapy for NSCLC.It can improve the depression state and enhance the QOL and sleep quality of the patients.
作者
苗斌
王清贤
张丽敏
MIAO Bin;WANG Qing-xian;ZHANG Li-min(Tangshan Hospital of Traditional Chinese Medicine,Tangshan 063000,China)
出处
《上海针灸杂志》
2020年第7期866-870,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
河北省中医药管理局科研计划项目(2018325)。
关键词
针刺疗法
癌
非小细胞肺
抑郁
五行
五音
匹兹堡睡眠质量指数
Acupuncture therapy
Carcinoma,Non-Small-Cell Lung
Depression
Five elements
Five sounds
Pittsburgh Sleep Quality Index
