摘要
目的 分析甲状腺功能亢进症孕妇采用丙硫氧嘧啶治疗的效果.方法 选择在本院进行孕期保健的88例孕妇为研究样本,其均患有甲状腺功能亢进症,同时研究时间均在2018年6月~2019年6月之间.采取随机数字排列表法将其分成为常规组与实验组,各44例,常规组孕妇给予基础保健措施,实验组孕妇给予基础保健措施及丙硫氧嘧啶口服治疗.对比两组孕妇干预前后血清TT3、TT4、FT3、FT4及TSH水平;对比每组新生儿结局.结果 干预后,实验组孕妇血清TT3、TT4、FT3及FT4水平均低于常规组,TSH水平高于常规组(P<0.05).实验组与常规组新生儿Apgar评分分别为(9.43±0.37)分、(7.51±0.39)分(P<0.05);实验组与常规组新生儿体重分别是(3035.76±203.18)g、(2189.62±187.03)g(P<0.05);实验组胎儿窘迫、早产以及甲状腺功能亢进症发生率均低于常规组(P<0.05).结论 甲状腺功能亢进症孕妇采用丙硫氧嘧啶治疗可显著改善其甲状腺功能以及新生儿预后,发挥一定作用.
Objective To analyze the therapeutic effect of propylthiouracil in the treatment of pregnant women with hyperthyroidism.Methods 88 pregnant women undergoing pregnancy care in our hospital were selected as study subjects,all of whom were diagnosed with hyperthyroidism.The study period was between June 2018 and June 2019.Random number table was used to divide them into the conventional group with 44 cases each and the experimental group with 44 cases.The pregnant women in the conventional group was given basic health measures.The experimental group was given basic health measures and oral administration of propylthiouracil.The serum TT3,TT4,FT3,FT4 and TSH levels were compared between the two groups of pregnant women before and after intervention;the neonatal outcomes were compared between the two groups.Results After the intervention,the serum levels of TT3,TT4,FT3 and FT4 in the pregnant women in the experimental group were lower than those in the conventional group,and the TSH levels were higher than those in the conventional group(P<0.05).Apgar scores of neonates in experimental group and conventional group were(9.43±0.37)points and(7.51±0.39)points respectively(P<0.05);the body weights of the newborns in the experimental group and the conventional group were(3035.76±203.18)g and(2189.62±187.03)g(P<0.05);the incidence of fetal distress,premature birth and hyperthyroidism in the experimental group was lower than that in the conventional group(P<0.05).Conclusion Propylthiouracil in the treatment of pregnant women with hyperthyroidism can significantly improve their thyroid function and the prognosis of neonates,which plays a certain role of application.
作者
洪海漫
HONG Haiman(Department of Obstetrics,Central Hospital Affiliated to Shenyang Medical College,Shenyang110000,China)
出处
《中国现代医生》
2020年第14期67-69,共3页
China Modern Doctor
