摘要
目的分析食管胃早期癌内镜特点和临床病理特征及其与淋巴结转移、浸润深度的相关性。方法选取济宁医学院附属医院2015年1月至2019年10月收治的100例食管胃早期癌患者为研究对象,研究记录食管胃早期癌患者内镜下的临床特点,分析临床病理特征,记录淋巴结转移和浸润深度的相关性。结果不同浸润深度患者的年龄、性别、肿瘤长径及浸润深度比较差异未见统计学意义(P>0.05);内镜下分型和组织分化程度比较差异有统计学意义(P<0.05),具有相关性。淋巴结转移与淋巴结未转移患者年龄、性别、内镜分型与肿瘤长径比较差异未见统计学意义(P>0.05),无相关性;分化程度和浸润深度比较差异有统计学意义(P<0.05),具有相关性。Logistic回归分析结果显示,淋巴结转移的危险因素为分化程度、浸润深度。患者内镜下分型主要为Ⅱb型,占36.00%(36/100)。低分化患者40例,中分化患者34例,高分化患者26例。肿瘤长径≤1 cm者34例(34.00%,34/100),2~3 cm者51例(51.00%,51/100),≥4 cm者15例(15.00%,15/100)。结论行内镜检查为诊断及发现食管胃早期癌的一种有效临床方法,分析内镜特点及临床病理特征能够在很大程度上对浸润深度进行提示,对判断淋巴结转移具有参考作用。
Objective To analyze the endoscopic characteristics and clinicopathological features of early esophageal and gastric cancer, and their relationships with invasion depth and lymph node metastasis.Methods One hundred patients with early esophageal and gastric cancer who were admitted to the Affiliated Hospital of Jining Medical University from January 2015 to October 2019 were enrolled as the research objects. The endoscopic characteristics of patients with early esophageal and gastric cancer were recorded. The pathological features of the disease were analyzed, and its correlations with lymph node metastasis and invasion depth were recorded.Results There were no significant differences in age, gender, tumor major diameter or depth of invasion among patients with different depths of invasion (P>0.05), but there were significant differences in endoscopic classification and tissue differentiation among them (P<0.05). There was no significant difference in age, gender, endoscopic classification or tumor diameter between patients with lymph node metastasis and patients without lymph node metastasis (P>0.05);but there was a significant difference in the degree of differentiation or the depth of infiltration (P<0.05). The results of logistic regression analysis showed that the risk factors of lymph node metastasis were differentiation degree and invasion depth. The endoscopic classification of patients was mainly type Ⅱb, accounting for 36.00% (36/100). There were 40 cases of low differentiation, 34 cases of middle differentiation and 26 cases of high differentiation. Thirty-four cases (34.00%, 34/100) were with tumor major diameter≤1 cm, 51 cases (51.00%, 51/100) were with tumor major diameter≥4 cm, 15 cases (15.00%, 15/100) were with tumor major diameter≥4 cm.Conclusions Endoscopic examination is an effective clinical method for the diagnosis and detection of early esophageal and gastric cancer. Analyzing endoscopic charalteristics and clinicopathological features can largely indicate the depth of invasion, which plays a reference role in judging lymph node metastasis.
作者
张曜文
艾宽宽
刘素芹
马翠梅
孙富强
王一波
Zhang Yiwen;Ai Kuankuan;Liu Suqin;Ma Cuimei;Sun Fuqiang;Wang Yibo(Department of Gastroenterology,Affiliated Hospital of Jining Medical University,Jining 272001,China)
出处
《中国实用医刊》
2020年第3期49-51,共3页
Chinese Journal of Practical Medicine
关键词
食管胃早期癌
内镜特点
病理特征
Early esophageal and gastric cancer
Endoscopic features
Pathological features
