摘要
目前,HBV感染是全球公认的肝细胞癌(HCC)主要危险因素。然而,在乙型肝炎-肝硬化-肝癌的发展过程中,还有其他的辅助因素,如性别、年龄、家族史、ALT/AST、吸烟饮酒史、代谢综合征以及合并HCV、HIV感染等可能独立或与HBV协同促进HCC的发生。综述了HBV相关HCC的危险因素研究进展。
At present,hepatitis B virus(HBV)infection is recognized as an important risk factor for hepatocellular carcinoma(HCC)in the world;however,during the development and progression of hepatitis B,liver cirrhosis,and liver cancer,other factors may promote the development of HCC independently or synergistically with HBV,such as sex,age,family history,alanine aminotransferase/aspartate aminotransferase,smoking and drinking history,metabolic syndrome,and HCV or HIV infection.This article reviews the research advances in the risk factors associated with HCC.
作者
任丹丹
刘娜
周路路
张楠
李春霞
东冰
徐光华
REN Dandan;LIU Na;ZHOU Lulu;ZHANG Nan;LI Chunxia;DONG Bing;XU Guanghua(Department of Infectious Diseases,Affiliated Hospital of Yan’an University,Yan’an,Shaanxi 716000,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2020年第7期1634-1638,共5页
Journal of Clinical Hepatology
基金
延安市科技惠民计划项目(HM2009-04)。
关键词
乙型肝炎病毒
癌
肝细胞
危险因素
hepatitis B virus
carcinoma
hepatocellular
risk factors
