摘要
目的探讨经颅黑质超声、非运动症状评估联合在早期帕金森病患者中的诊断应用价值。方法本次研究对象选取我院于2019年1月至2020年3月收治的42例早期帕金森病患者,随机分为A组、B组和C组,三组分别为13例、12例、17例,A组患者接受经颅脑黑质检查,B组患者接受非运动症状评估检查,C组患者接受经颅黑质超声、非运动症状评估联合诊断,对比三组患者诊断的特异性、敏感性和阳性预测值。结果 A患者的特异性、敏感性和阳性预测值分别为84.49%、86.2%和87.46%,而B患者的特异性、敏感性和阳性预测值是和75.49%、70.41%和81.86%,C组患者特异性、敏感性和阳性预测值是89.62%、87.34%和94.79%,差异具有统计学意义(P<0.05)。结论经颅黑质超声、非运动症状评估联合使用可以用于早期帕金森患者的诊断,且特异性和灵敏度均较高,值得临床推广。
Objective To investigate the diagnostic value of transcranial black matter ultrasonography and nonmotor symptom assessment in early Parkinson's disease patients.Methods 42 patients with early Parkinson's disease who were admitted to our hospital from January 2019 to March 2020 were randomly divided into group A,group B,and group C.The three groups were 13 cases,12 cases,and 17 cases respectively.Group A patients received transcraniocerebral examination.Group B patients were examined for non-motor symptoms,and group C patients were diagnosed with transcranial black matter ultrasound and non-motor symptom evaluation.The specificity,sensitivity,and positive prediction values of three groups of patients were compared.Results The specificity,sensitivity and positive predictors of patients A were 84.49,86.2 and 87.46,respectively,while the specificity,sensitivity and positive predictors of patients B were 75.49,70.41 and 81.86.The specific,sensitive and positive predicted values of group C were 89.62,87.34 and 94.79,and the difference was statistically significant(P<0.05).Conclusion The combined use of transcranial ultrasound and non-motor symptom evaluation can be used in early diagnosis of Parkinson's disease,and the specificity and sensitivity are high,which is worthy of clinical promotion.
作者
富璐
FU Lu(Department of Ultrasound,Health Medicine Center,Dalian Central Hospital,Dalian 116033,China)
出处
《中国医药指南》
2020年第19期133-134,共2页
Guide of China Medicine
关键词
早期帕金森病
经颅黑质超声
非运动症状评估
特异性
敏感性
阳性预测值
Early Parkinson's disease
Transcranial black ultrasound
Non-motor symptom assessment
Specificity
Sensitivity
Positive Prediction
