摘要
雷公藤是从中药中挖掘出的一项疗效显著、用途广泛且极具发展前途的新药,在民间主要用于杀虫解毒以及关节炎和皮肤病的治疗中。近年来,其作为一种新型药剂在临床上应用,包括泌尿系统疾病、系统性红斑狼疮、类风湿性关节炎等病。虽治疗效果较为显著,但其具有较为明显的毒副作用,主要表现为消化系统反应、肝肾功能损害、生殖系统损害等,因此积极探索雷公藤减毒方法十分重要。本文阐述了雷公藤的毒性机理、中药配伍减毒方法,目的为提高临床用药安全性。
Tripterygium wilfordii is a new drug with remarkable curative effect,wide application and great development prospect in TCM,which is mainly used in insecticidal detoxification,arthritis and skin disease.In recent years,it has been used as a new drug in clinic,including urinary system disease,systemic lupus erythematosus,rheumatoid arthritis and so on.Although the therapeutic effect is remarkable,it has obvious toxic and side effects,mainly manifested in digestive system reaction,liver and kidney function damage,reproductive system damage and so on.Therefore,it is very important to actively explore the detoxification method of Tripterygium wilfordii.In this paper,the toxic mechanism of Tripterygium wilfordii,the method of reducing toxicity by combination of Traditional Chinese Medicine were described to improve the safety of clinical drug use.
作者
彭德明
PENG De-ming(Department of Pharmacy,affiliated Hospital of Nankai University,Tianjin 300071,China)
出处
《中国处方药》
2020年第7期20-22,共3页
Journal of China Prescription Drug
关键词
雷公藤
毒性机理
配伍
中药
减毒
Tripterygium wilfordii
Toxicity mechanism
Compatibility
Traditional Chinese medicine
Detoxification
