摘要
目的探讨LEEP治疗CIN合并高危型HPV感染的近期疗效。方法选择本院2018年1月—2018年12月收治的100例宫颈上皮内瘤变合并高危型人乳头瘤病毒持续感染的患者作为研究对象,根据随机原则进行分组,各组为50例,观察组患者月经干净后3天,施行超高频电波刀手术(LEEP),对照组患者月经干净后3天,施行宫颈冷刀锥切术(CKC),比较两组患者的手术指标,包括术中出血量、手术的时间、切口愈合的时间;评估和比较两组患者的治疗疗效。结果 (1)观察组术中出血量明显比对照组更少,手术的时间、切口愈合的时间明显比对照组更短,P <0.05。(2)观察组宫颈上皮内瘤变的治疗效果明显比对照组更优,P <0.05。(3)观察组HPV感染的治疗效果明显比对照组更优,P <0.05。结论 CIN合并高危型HPV感染患者施行LEEP的治疗疗效确切,效果优于传统手术,患者术后恢复更快,有利于改善患者的预后。
Objective To investigate the short-term efficacy of LEEP in the treatment of CIN complicated with high-risk HPV infection.Methods 100 patients with cervical intraepithelial neoplasia complicated with persistent high-risk human papillomavirus infection admitted to our hospital from January 2018 to December 2018 were selected as the research objects.According to the principle of randomization,50 patients in each group were divided into two groups.The patients in the observation group underwent ultra-high frequency wave knife surgery(LEEP)three days after their menstruation was clean.The patients in the control group were divided into two groups.Three days after menstruation,patients underwent cold knife conization(CKC)of the cervix.The operative indicators of the two groups were compared,including the amount of bleeding during operation,the time of operation and the time of wound healing.The therapeutic effects of the two groups were evaluated and compared.Results(1)The amount of bleeding in the observation group was significantly less than that in the control group,and the time of operation and wound healing was significantly shorter than that in the control group,P<0.05.(2)The therapeutic effect of cervical intraepithelial neoplasia in the observation group was significantly better than that in the control group(P<0.05).(3)The therapeutic effect of HPV infection in the observation group was better than that in the control group(P<0.05).Conclusion LEEP is effective for patients with CIN combined with high-risk HPV infection,which is superior to traditional surgery.The patients recover faster after operation,and it is beneficial to improve the prognosis of patients.
作者
金昌霞
周树平
JIN Changxia;ZHOU Shuping(Department of Gynecology,Maternal and Child Health Hospital,Ezhou Hubei 436000,China;Department of Pediatrics,Maternal and Child Health Hospital,Ezhou Hubei 436000,China)
出处
《中国继续医学教育》
2020年第20期140-142,共3页
China Continuing Medical Education
