摘要
目的:研究清热化湿和胃汤对脾胃湿热慢性胃炎(CG)患者疗效及中医证候、幽门螺杆菌(Hp)根除率的影响方法:2017年10月~2018年10月我院收治的126例脾胃湿热型CG患者,分为观察组和对照组各63例,观察组采用清热化湿和胃汤治疗,对照组采取三联疗法(克拉霉素+阿莫西林+埃索美拉唑肠溶胶囊)治疗,观察比较两组临床鳞屑、中医证候积分、Hp根除情况及胃镜检查分级程度。结果:观察组总有效率(96.83%)明显高于对照组(87.30)(P<0.05);治疗前,两组中医证候积分、胃镜检查分级程度比较差异无统计学意义(P>0.05);治疗后,两组中医证候积分与治疗前比较显著下降义(P<0.05),观察组中医证候积分显著小于对照组(P<0.05);观察组Hp根除率(88.87%)显著大于对照组(63.49%),差异具有统计学意义(P<0.05);治疗后,两组胃镜检查分级程度与治疗前比较差异具有统计学意义(P<0.05),观察组胃镜检查分级程度为无、轻度患者比例显著大于对照组,中度、重度患者比例显著小于对照组,差异具有统计学意义(P<0.05)。结论:清热化湿和胃汤治疗脾胃湿热型CG疗效显著,能有效提高Hp根除率,改善患者中医证候及胃镜成像。
Objective:To investigate the effect of Qingre Huashi Hewei Decoction on the curative effect, TCM syndrome and Helicobacter pylori(Hp) eradication rate for chronic gastritis(CG) patients with spleen-stomach damp-heat syndrome.Methods:126 cases of spleen-stomach damp-heat type CG treated in our hospital from October 2017 to October 2018 were selected, and divided into two groups, each with 63 cases.The observation group was treated with Qingre Huashi Hewei Decoction, while the controlled group was treated with triple therapy(Clarithromycin+Amoxicillin+Omeprazole Enteric-coated Capsule).Then the clinical scales, TCM syndrome scores, Hp eradication and gastroscopy grades were recorded in both groups.Results:The total effective rate of the observation group was significantly higher than that of the controlled group(96.83% vs 87.30, P<0.05);No significant difference was found in the TCM syndrome scores and gastroscopy grades between groups(P>0.05).After treatment, the TCM syndrome scores were decreased in both groups, and were lower in the observation group than in the controlled group(P<0.05).The eradication rate of Hp in the observation group was significantly higher than that in the controlled group(88.87% vs 63.49%, P<0.05).After treatment, the gastroscopy showed that the observation group had higher proportions of mild degree patients, as well as lower proportions of moderate and severe patients than those of the controlled group(P<0.05).Conclusion:Qingre Huashi Hewei Decoction can effectively improve the Hp eradication rate and ameliorate TCM syndrome and gastroscopic imaging for spleen-stomach damp-heat type CG patients.
作者
罗芳
蔡林
陈光华
舒波
LUO Fang;Cai Lin;CHEN Guanghua(Traditional Chinese Medicine Room,the Affiliated Hospital of North Sichuan Medical College,Nanchong Sichuan 637000,China;Department of Traditional Chinese Medicine,the Affiliated Hospital of North Sichuan Medical College,Nanchong Sichuan 637000,China)
出处
《四川中医》
2020年第6期117-120,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
四川省卫生厅科研基金(编号:110423)。
关键词
脾胃湿热慢性胃炎
清热化湿和胃汤
中医证候
HP根除率
疗效
Spleen-stomach damp-heat chronic gastritis
Qingre Decoction
TCM syndromes
Hp eradication
Effect
