摘要
目的:探讨三阴性乳腺癌(TNBC)的MRI表现、TIC类型、ADC值与肿瘤大小、组织病理学分级、淋巴结转移之间的相关性。方法:收集经病理证实的TNBC患者102例,均行乳腺MRI平扫、DWI和动态增强扫描。比较TNBC不同肿瘤大小、组织病理学分级、有无淋巴结转移的MRI表现和参数。肿瘤大小、组织病理学分级、淋巴结转移与TIC类型及ADC值的相关性行Spearman相关分析。结果:不同肿瘤大小(T1、T2、T3)、不同组织病理学分级(Ⅰ~Ⅱ级、Ⅲ级)、有无淋巴结转移患者的肿块形态、边缘、强化特征、T2WI信号差异均无统计学意义(均P> 0.05)。组织病理学分级、淋巴结转移与TIC分型及ADC值均有相关性(均P<0.05)。结论:TIC分型越高或ADC值越低,TNBC的组织病理学分级越高,淋巴结转移的风险越大。
Objective:To investigate the correlation between MRI performance,TIC,ADC value and tumor size,histopathological grades,lymph node metastasis in patients with triple-negative breast cancer(TNBC).Methods:A total of 102 patients with TNBC who underwent MRI and then confirmed with pathology in our hospital were chosen to study.All patients underwent breast MRI plain scan,DWI,and dynamic contrast-enhanced MRI.MRI features and parameters were compared between TNBC patients with different tumor sizes,histopathological grades,or with or without lymph node metastases,and Spearman analysis was used for correlation.Results:There were no significant differences between TNBC patients with different tumor sizes(T1,T2,T3),histopathological grades(grades Ⅰ ~ Ⅱ,Ⅲ ),and with or without lymph node metastases on the lesion morphology,margins,enhancement characteristics,T2 WI signal(all P> 0.05).The histopathological grade,and lymph node metastasis were correlated with TIC or ADC value.In particular,the correlations between histopathological grade,lymph node metastasis and TIC and ADC were statistically significant(all P<0.05).Conclusions:For TNBC patients,the higher the TIC classification or the lower the ADC value,the histopathological grades may be higher,the risk of lymph node metastasis may be greater.
作者
李丽
郑玉荣
张静
马玉荣
梁娟
刘光耀
LI Li;ZHENG Yurong;ZHANG Jing;MA Yurong;LIANG Juan;LIU Guangyao(Department of MRI,Second Hospital Affiliated of Lanzhou University,Lanzhou 730030,China)
出处
《中国中西医结合影像学杂志》
2020年第4期374-378,共5页
Chinese Imaging Journal of Integrated Traditional and Western Medicine
关键词
乳腺肿瘤
肿瘤
组织学类型
淋巴转移
Breast neoplasms
Neoplasms by histologic type
Lymphatic metastases
