摘要
目的分析在当今临床中治疗围绝经期功能失调性子宫出血的实际效果。方法对该院在2018年4月—2019年8月收治的76例患者进行试验研究,采用数字法对所有研究患者进行分组,每组患者38例,讨论组患者采用米非司酮治疗,参照组患者采用黄体酮治疗,对比两种不同药物在治疗绝经期功能失调性子宫出血疾病的最终效果。结果经统计学软件对两组患者治疗后治疗效率进行对比,讨论组患者总有效率97.37%高于参考组总有效率78.95%,差异有统计学意义(χ2=6.176,P<0.05)经统计学软件对两组患者服药后不良反应发生概率分析,讨论组患者服药后不良反应发生概率10.52%低于参考组患者服药后不良反应发生概率28.94%,差异有统计学意义(χ2=4.070,P<0.05),讨论组患者治疗满意度97.36%高于参考组患者治疗满意度81.58%,差异有统计学意义(χ2=5.029,P<0.05),发现讨论组患者各项指标情况均好于参考组(P<0.05),讨论组患者性激素指标情况均好于参考组(P<0.05)。结论治疗围绝经期功能失调性子宫出血疾病中应用米非司酮药物的最终治疗效果显著,患者出现不良反应现象较少,且性激素水平得到明显改善,治疗效果得到理想程度。
Objective To analyze the actual effect of perimenopausal dysfunctional uterine bleeding in clinical practice today.Methods A total of 76 patients who were treated in the hospital from April 2018 to August 2019 were studied in a trial manner.All patients were grouped by numerical methods,with 38 patients in each group.The patients in the discussion group were treated with mifepristone.Patients in this control group were treated with progesterone,and the final effects of two different drugs in treating menopausal dysfunctional uterine bleeding were compared.Results The treatment efficiency of the two groups was compared by statistical software.The total effective rate of the patients in the discussion group was 97.37% higher than the total effective rate of the reference group by78.95%,the difference was statistically significant(χ2=6.176,P<0.05).The software analyzes the probability of adverse reactions after taking medicine in two groups of patients.The probability of adverse reactions after taking medicine in the discussion group was10.52% lower than that in the reference group.The incidence of adverse reactions after taking medicine was 28.94%,the difference was statistically significant(χ2=4.070,P<0.05)the treatment satisfaction of the patients in the discussion group was 97.36% higher than that of the reference group,and the treatment satisfaction was 81.58%(χ2=5.029,P<0.05);After treatment the indicators of the patients in the discussion group were better than the reference group(P<0.05).the sex hormone indicators of the patients in the discussion group were better than those in the reference group(P<0.05).Conclusion The final treatment effect of mifepristone in the treatment of perimenopausal dysfunctional uterine bleeding is significant,the patients have fewer adverse reactions,and the levels of sex hormones are significantly improved.The therapeutic effect is ideal,so it is worthy of clinical medicine.
作者
冯会兵
FENG Hui-bing(Department of Obstetrics and Gynecology,Maternal and Child Health and Family Planning Service Center,Jining,Shandong Province,272200 China)
出处
《世界复合医学》
2020年第5期19-21,31,共4页
World Journal of Complex Medicine