摘要
目的观察温阳宣肺疏肝法治疗抑郁性神经症的临床疗效。方法将2018年3月—2019年5月河北省中医院内科接诊的180例抑郁性神经症患者随机分为治疗组98例和对照组82例,治疗组口服基于温阳宣肺疏肝法的解郁汤,对照组口服盐酸帕罗西汀片,2组均连续治疗3个月,统计2组患者临床疗效,观察2组治疗前后汉密尔顿抑郁量表(HAMD,24项)评分、抑郁自评量表(SDS)评分、中医症状等级量表评分及Asberg药物不良反应量表评分变化情况。结果治疗组总有效率为94.9%(93/98),明显高于对照组的81.7%(67/82),差异有统计学意义(P<0.05);2组治疗后HAMD、SDS评分及中医症状等级量表评分均明显低于治疗前(P均<0.05),且治疗组中医症状评分明显低于对照组同期(P均<0.05);2组治疗后Asberg药物不良反应量表评分均较治疗前明显降低(P均<0.05),且治疗组降低程度更明显(P<0.05)。结论温阳宣肺疏肝法治疗抑郁性神经症临床疗效肯定,可以明显改善患者的抑郁情绪及主要症状,且不良反应少。
Objective It is to observe the clinical effect of Wenyang Xuanfei Shugan method on depressive neurosis.Methods 180 patients with depressive neurosis who were treated in the outpatient clinic of the Chinese Medicine Hospital of Hebei Province from March 2018 to May 2019 were selected as the research objects,and they were divided into a treatment group(98 cases)and a control group(82 cases)according to the random number table method.The treatment group was treated with Chinese medicine Jieyu decoction based on Wenyang Xuanfei Shugan method,and the control group was treated with paroxetine hydrochloride tablets.Both groups were treated continuously for 3 months.The clinical efficacy of the two groups was assessed.The changes of scores of Hamilton Depression Scale(HAMD)(24 items),Depression Self-Assessment Scale(SDS),TCM Syndrome Rating Scale and Asberg Drug Adverse Reaction Scale before and after treatment were observed in the two groups.Results The total effective rate in the treatment group was 94.9%(93/98),significantly higher than 81.7%(67/82)in the control group(P<0.05);the scores of HAMD,SDS and TCM syndrome scale after treatment in the two groups were significantly lower than those before treatment(P<0.05),and the score of the treatment group were significantly lower than that of the control group(P<0.05);the scores of the Asberg Drug Side Reaction Scale after treatment in both groups were significantly lower than that before treatment(P<0.05),and the degree of reduction in the treatment group was more obvious(P<0.05).Conclusion The clinical effect of Wenyang Xuanfei Shugan method on depressive neurosis is definite,it can significantly improve the patients’depression and main symptoms with less side effects.
作者
张丽芸
董璐
高赫
孙福军
成立
ZHANG Liyun;DONG Lu;GAO He;SUN Fujun;CHENG Li(Graduate School of Hebei College of Traditional Chinese Medicine, Shijiazhuang 050091,Hebei,China)
出处
《现代中西医结合杂志》
CAS
2020年第21期2306-2309,2315,共5页
Modern Journal of Integrated Traditional Chinese and Western Medicine
基金
河北省科技支撑计划项目(14277773D)。
关键词
抑郁性神经症
温阳宣肺疏肝法
解郁汤
depressive neurosis
Wenyang Xuanfei Shugan method
Jieyu decoction
