摘要
目的探讨比较阿卡波糖与二甲双胍治疗糖尿病前期门诊患者的效果。方法随机选取2018年10月至2019年10月本院门诊收治的92例糖尿病前期患者,平均分为甲组和乙组,每组46例。甲组患者运用阿卡波糖治疗,乙组患者运用二甲双胍治疗。对比两组患者糖尿病发生以及血糖控制情况。结果甲组患者糖尿病发生率为17.39%,明显低于乙组的60.87%,乙组血糖控制有效率高于甲组(P<0.05);两组患者治疗前空腹血糖(FPG)、餐后2h血糖(2h PG)及总胆固醇(TC)指标水平比较差异无统计学意义;治疗后,两组FPG、2h PG及TC指标水平均有显著改善,其中乙组FPG、TC指标低于甲组,2h PG高于甲组(P<0.05)。结论糖尿病前期门诊患者运用阿卡波糖与二甲双胍治疗,均能获得一定治疗效果,但与二甲双胍相比,阿卡波糖能够有效降低患者的餐后血糖水平,因此,在预防糖尿病发生方面,阿卡波糖比二甲双胍更加适合。
Objective To compare the effect of acarbose and metformin in the treatment of pre diabetes outpatients.Methods 92 patients with pre diabetes were randomly divided into group A and group B,with 46 cases in each group.Patients in group A were treated with acarbose,while patients in group B were treated with metformin.The occurrence of diabetes and the control of blood glucose were compared between the two groups.Results The incidence of diabetes in group A was 17.39%,which was significantly lower than that in group B(60.87%),while the effect of blood glucose control in group B was better than that in group A(P<0.05).There was no significant difference in fasting blood glucose(FPG),postprandial blood glucose(2 h PG)and total cholesterol(TC)between the two groups before treatment.After treatment,the FPG and TC of group B were better than those of group A,but the 2 h PG of group B was higher than that of group A(P<0.05).Conclusion Compared with metformin,acarbose can effectively reduce the postprandial blood glucose level of patients.Therefore,acarbose is more suitable than metformin in the prevention of diabetes.
作者
刘婷
陈强
陈珊
Liu Ting;Chen Qiang;Chen Shan(Department of Medicine,Yingtan Maternal and Child Health Hospital,Yingtan,Jiangxi,335000,China)
出处
《当代医学》
2020年第22期51-53,共3页
Contemporary Medicine
