摘要
目的分析探讨将拉贝洛尔应用于妊娠高血压患者治疗中的临床疗效。方法将2017年3月至2018年6月前来本院接受治疗的妊娠高血压患者99例对比实验中,运用区组随机化分组法将此99例患者随机分组,拉贝洛尔组(50例)及常规药物组(49例),拉贝洛尔组使用拉贝洛尔进行治疗,常规药物组行常规药物治疗,观察对比此两组患者的治疗效果、药后不良反应出现情况、受治后收缩压(SPB)、舒张压(DBP)、钙离子含量、镁离子含量及患者的分娩结局及新生儿情况。结果行拉贝洛尔进行治疗的拉贝洛尔组患者受治后收缩压(SPB)、舒张压(DBP)、钙离子含量、镁离子含量优于常规药物组,其治疗有效率及药后不良反应发生率优于常规药物组,其早产发生率、转剖宫发生率、胎儿Apgar评分、胎儿窒息发生率、宫内窘迫发生率优于常规药物组,此11项对比项经检验确定均有统计学意义(P<0.05)。结论在妊娠高血压患者的治疗中使用拉贝洛尔进行治疗,其治疗效果优于常规药物治疗,治疗效果佳,不良反应小,可在临床妊娠高血压患者的治疗中推广应用。
Objective To analyze the clinical efficacy of labetalol in the treatment of pregnant hypertension patients.Methods 99 pregnant hypertension patients who came to the hospital for treatment were randomly grouped into groups of 99 patients,labetalol group(50 cases)and conventional drug group(49 cases).The labetalol group was treated with labetalol,and the conventional drug group was treated with conventional drugs.The results of the two groups of patients were compared,the adverse reactions after the drug,the systolic pressure(SPB),diastolic pressure(DBP),calcium content,magnesium content,birth outcome and neonatal conditions.Results The patients of labetalol group were treated with labetalol,systolic pressure(SPB),diastolic pressure(DBP),calcium content,and magnesium content better than the conventional drug group,and their treatment efficiency was higher than that of the conventional drug group.The incidence of adverse reactions was better than that of the conventional drug group.The incidence rate of premature birth,the incidence of autopsy,the fetal Apgar score,the incidence of fetal asphyxia,and the incidence of intrauterine distress were superior to the conventional drug group.These 11 comparative items were determined to be statistically signiificant(P<0.05).Conclusion Labetalol was used in the treatment of pregnant hypertension patients,and its therapeutic effect was better than that of conventional drugs.The therapeutic effect was good,and the toxicity and side effects were small.It could be used in the treatment of pregnant hypertension patients.
作者
王宏
WANG Hong(Benxi City Central Hospital,Benxi 117000,China)
出处
《中国医药指南》
2020年第20期105-106,共2页
Guide of China Medicine
关键词
拉贝洛尔
常规药物
对比实验
妊娠高血压
胎儿结局
血压水平
治疗效果
Labetalol
Conventional drugs
Comparative experiments
Pregnancy hypertension
Fetal outcome
Blood pressure level
Therapeutic effect
